Hi Tony,
Nice to see a fellow Liverpudlian on here, (though I am sorry that you need to be here).
I was diagnosed in July 2015 and was put on Degarilex immediately. I did react to it quite badly some months, but my onco told me that if I stopped it, I would feel much worse. Hence I carried on with it for more than two years, even though its effectiveness diminished over time and my PSA began to rise dramatically.
I started a course of Docetaxel chemotherapy in October last year and my first session of chemo coincided with my Degarlex injection. The combination of the two did me no good at all and I ended up in hospital overnight. So I finally managed to convince the onco that I should stop the Degarlilex. He put me on to Decapeptyl instead and I find this much easier to cope with (though I am not sure how its effectiveness compares).
I have now finished the chemotherapy and I have been feeling so much better, though my PSA is rising again, so it is time to consider further treatment options.
I understand your fears regarding fracture or compression. I am the same. I have extensive mets in my spine and particularly my pelvic area, though not, as far as I know, as far as my skull. I do find that I am unable to bend sufficiently to pick anything up off the floor and I avoid any heavy lifting. I also started using a walking stick from very early on, mainly as a safeguard against losing balance and falling. To do so could be devastating to someone in our position.
If you are tolerating Degarelix well, I would stay on it. It is clearly the best HT treatment available (and not everyone gets the chance of having it because of the expense) But I think for me, I would prefer the Decapeptyl.
We are all different!
Best wishes
Peter