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Devastating News

User
Posted 17 Oct 2016 at 23:02
Hi Lyn - thank you for replying and for the drug info.

We already know that the original back pain was due to severe disc damage - a number of different scans and MRIs confirmed this at the time. What we don't know is if the pain from that masked cancer pain too.

User
Posted 19 Oct 2016 at 11:35
We have had some more difficult news. The repeat of the PSA test showed an increase of 700 up to 6700 in a week. I am finding it very difficult to cope with this as it obviously indicates very aggressive growth.

Does anyone know if there is still a chance that the hormone treatment could reduce the PSA or is that unlikely ?

User
Posted 19 Oct 2016 at 15:03

Sorry but I don't know a specific answer but if the first zoladex jab was last Friday and you have a new PSA test a few days ago the zoladex has not had a chance to get going. The zoladex is more powerful than the biclutamide in getting PSA down normally.
As for the rise itself, it looks bad because the numbers are so high to start with however what it does indicate is that the PSA increased by 11% in a week. Whilst that is not great it would indicate that the doubling time of the cells is 9 weeks, some peoples double every week ( mine did briefly before the drugs started to work although my score was much lower in the first place).
Remember your dads situation has not been spotted until it has had a chance to get to 6,000, to put it in perspective, if it had been 12 last week it would now be 13.
Everyone is different and I totally understand why everyone is concerned, maybe the zoladex won't work or maybe it will work spectacularly ( mine went from 342 to 8 in 3 months) , at this stage you sadly need to wait and see.
The docs may have other ideas as to other intervention now but they may also want to wait.
The results from the scans will help understand, the biopsy is likely to confirm there is a lot if quite fast growing cancer but you kind of know that already, it's the MRI that will show you the spread and then they can plan how to target it.
Right now ( and this is easy to say) just try to be together as a family as much as you can and enjoy each day you can, let ignorance be bliss rather than sad.
My thoughts are with you and your family
Kev

Dream like you have forever, live like you only have today Avatar is me doing the 600 mile Camino de Santiago May 2019

User
Posted 19 Oct 2016 at 15:27
Thank you for the thoughtful reply Kev.

(It's my husband not my dad)

He has just had the biopsy and they only took 4 cores to grade the cancer.

I'm assuming this is because the MRI showed cancer all over the prostate so there was no point doing any more :-(

I was going to ask if anyone else has had only a 4 core biopsy but I feel that I am increasingly clutching at straws.

User
Posted 19 Oct 2016 at 21:01

Hi Sallyyy - just picked up on your messages - my o/h diagnosed Xmas Eve and had his first injection then - he was referred to Oncology and put on STAMPEDE Trial.  His PSA over 4,000 and Gleason 4 - he has done really well and Oncologist and support staff marvellous particularly the Sisters' at The Hospital.  The cancer kept itself so well hidden and I felt and still do quite angry with it - stupid really but I have to be honest.  However, people are so supportive on this web site and it has given me courage and comfort in the fight - the o/h won't discuss this much!!  So, when people say there is hope, there really is - so you take care and take courage.  I dip in and out of this site am a bit of a nerd with this technology, and hope that's made you smile a bit !  Take care

User
Posted 19 Oct 2016 at 21:06

Okay - was the new PSA test done at the same time or just after the biopsy? If so, much of the rise could be down to that. It is too early for the PSA to be sinking rapidly with the hormone treatment - HT needs a bit longer to work because it starves the cancer rather than killing it.

I don't think you are at the stage of straw clutching yet - as said above, try to do happy things and put the guessing to one side for a little while. After your next appointment you will have a clearer idea of what is happening.

"Life can only be understood backwards; but it must be lived forwards." Soren Kierkegaard

User
Posted 19 Oct 2016 at 21:20
Sorry I should have been clearer. The 2nd PSA test was done a week ago (one week after the original test) but we only got the result today. It was 2 days before starting the hormone tablets so we knew there was no possibility of an improvement - but we were just upset that it had risen so dramatically in 7 days from what was already a very high point.

Thank you for adding your story Jackie. I'm glad your husband is doing ok on his treatment

x

Edited by member 20 Oct 2016 at 22:41  | Reason: Not specified

User
Posted 20 Oct 2016 at 14:51

Thanks Sallyyy - take heart Lynne E has it on button as it were - and we are in the club no one really wants to join.   By for now and take care xx

 
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