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What's a high Psa level?

User
Posted 14 Feb 2015 at 18:10
My dad was diagnosed with prostate cancer in 2010, and I'm still no wiser to what is happening. He is now 72 and has not had any treatment as he was told his cancer was not doing anything n would probably die of old age before his cancer did anything. Would he be advised of this or is he burying his head in the sand? In 2012 I started logging his Psa counts n it was 8.6, his last result in nov 14 is 16.1, which is his highest count and he has now been told the cancer is larger n he's now waiting for a biopsy appt to come through.

When he was first diagnosed he was told his Psa was very high... But it's now at its highest so far. So what is classed as a high Psa? And why would u not have treatment from the off? I feel so frustrated by this n every hospital appt stresses me out to the max so I know it must be hard on him too with all the worry.

User
Posted 14 Feb 2015 at 22:37

Hi Tetley, for a man in his 50s a PSA above 3.0 would be considered higher than it should be and for a man in his 70s a PSA of 4 or 5 would perhaps trigger a biopsy. However, there are men diagnosed with a PSA in the hundreds and the highest we have had here was 13,000. Even so, it isn't the PSA that determines what should happen next, it would be down to his Gleason score (which was determined at the biopsy)

It seems your dad is on Active Surveillance (AS) which menas that he has regular PSA tests and probably an annual biopsy, scan & DRE. My guess is that your dad's Gleason is G(3+3) 6 or G(3+4) 7 and/or that the biopsy & scans showed he had a very early stage tumour (a T score of T1 or perhaps T2a???) in which case AS may have been what your dad wanted and was advised would be his best option. There are many reasons why men choose AS including a desire to avoid what can be pretty appalling side effects (bearable if your cancer is a problem but an unnecessary difficulty if the cancer is so small that it is unlikely to cause any problems.) My father-in-law chose AS because he didn't want to risk being impotent, for example. The important thing about AS is making sure that regular checks are done in case it starts to progress - it sounds like this is what your dad's specialist is doing - hopefully all is well and your dad can carry on with the AS.

Try not to be stressed about it - download the toolkit from the home page of this site and then ask dad whether he still has a copy of the diagnosis letter. If not, his GP would be able to tell him what his last G & T scores were and then when he gets his next results you will have a better idea of how things are going and whether AS is still the right choice for him.

"Life can only be understood backwards; but it must be lived forwards." Soren Kierkegaard

User
Posted 14 Feb 2015 at 22:45

Hi Tetley,

It rather looks like your Dad initially had a PSA that might not have been considered very high and was put on surveillance as he had subsequent PSA tests. I would have thought that at 8.6 in 2012 a biopsy might have been done at that point plus a MRI scan. Where there no PSA tests between 2012 and 2013? I can certainly understand why at 16.1 he is now having a Biopsy. Much will now depend on the biopsy and most likely an MRI and possibly a bone scan to make a diagnosis. Dependent on this he may be offered various treatments. For a man with a PSA of 16.2 unless there is another reason for this, I would think treatment would not be before time. PSA can go into the thousands for those with advanced PCa but for a man of his age 8.6 should have resulted in more frequent monitoring if not biopsy.

Barry
User
Posted 15 Feb 2015 at 09:11

Morning Tetley.
My husband's PSA started at 5.7 when he was in his early 70s.
He opted for Active surveillance because he had no symptoms and was worried about side effects of treatment.
He was told by his nurse when she informed us he had cancer that he was likely to die with it not of it as it was a slow grower.
Fast forward a year and the PSA went up to 6.3 and we were advised to think in terms of treatment.
Last June, at age 73, he had Low Dose Seed Brachytherapy.
Just to confirm that your dad was in all probability told the same regarding where the cancer was going so no, he wasn't burying his head in the sand.

My husband was monitored throughout the Active Surveillance period so I am assuming it was the same for your dad? PSAs, biopsies?

We can't control the winds - but we can adjust our sails
User
Posted 15 Feb 2015 at 12:49

Barry, I read it that the dad has had a few PSAs which Tetley has been keeping a record of, and this latest one is the highest?

"Life can only be understood backwards; but it must be lived forwards." Soren Kierkegaard

User
Posted 15 Feb 2015 at 15:41

No mention of PSA between when first logged in 2012 and latest in 2014 in post or profile. It would be interesting if there were tests done to see progression. But this is really academic now other than perhaps to help understand why no further tests scans or biopsies were done previously (that we are told of anyway). What we do know is that a biopsy is now being done and this and any other scans should establish diagnosis and what treatment options there are.

Barry
User
Posted 18 Feb 2015 at 19:05
Hi all

Thankyou soo much for your replies.

Dads psa's have been-

Mar 2012: 8.6

Aug 2012: 15.7

Oct 2012: 11.6

May 2013: 10.4

Aug 2013: 13.5

Nov 2013: 13

Jun 2014: 14.2

Nov 2014: 16.1

This is all of his readings he has had since 2012.

He doesn't recall being told about Gleason counts but now i know about that part iwill keep an eye out for this on his letter. (if he ever gets the appt for his biopsy. He's been told it will be next month - it seems to take forever when your waiting)

I only remember him having one other biopsy before now but he says he's had at least 2.

Sorry I don't know any more info than this, I've never had to deal with knowing the ins n outs before. it was too late for my grandad (dads dad) who died of cancer within a couple of weeks of diagnosis 20 odd years ago.

User
Posted 18 Feb 2015 at 20:03

Hello Tetley,

Sorry to read that your dad's readings are prompting further intervention, but glad that something is being considered.

In 2010 he was diagnosed and it was thought to be a pussycat cancer, slow grower that he would "die with" not "from". It is quite likely that he was told that and was not burying head in sand. Unfortunately pussycats can become tigers it seems.

A couple of factors that you and he might want to consider when you start to look at treatment options. What is the life expectancy in your family line? This may affect his treatment choices?

You should be able to obtain detail of previous biopsies, ask your GP.

Lots of options for him it seems, so take heart.

atb

dave

User
Posted 18 Feb 2015 at 20:56

I would have thought that with a set of PSA results like these, your dad might continue with the AS ... as long as the biopsy doesn't suggest that the Gleason has changed dramatically. It is up & down enough to wonder about prostatitis. I wouldn't be too anxious at this stage.

"Life can only be understood backwards; but it must be lived forwards." Soren Kierkegaard

 
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