I have had seven three monthly Zoladex injections all using freeze spray and all totally pain free.
I did have a strange incident with the one I had to get just before I went on holiday this year. The nurse put the freeze spray on the area and proceeded to inject the pellet, when she withdrew the injection the pellet came straight back out. She said she had never seen anything like it before. This resulted in a frantic phone around local chemists to see if anyone had a spare injection as I was leaving to go on holiday the next morning, most don't carry any extra as they are so expensive (£1,000 I think she said). She managed to find one chemist who only had a monthly injection so I went and collected it and it was administered without any problem. I went and got my next three monthly injection the following month and that was also administered without any problem.
I have also tolerated Zoladex very well with only the occasional flush, I think my last injection will be in October as that will be the eighth and I was told I would be on it for two years.
I was diagnosed Dec 2013 (PSA 59, T2C contained), I started Zoladex Injections in Feb 2014 and had EB Radiotherapy in July/August 2014 and flew through it with no issues, my latest PSA is still less than 0.2 which Oncologist is very happy with.
Gerry.