Could Previous biopsy have missed cancer

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User

Posted 05 Oct 2015 at 15:46

Well, after a scare 5 years ago, I hoped I would not be returning - despite some wonderful support!

5 years ago 14 biopsy samples all clear, slowly rising PSA but nothing dramatic until a 10.5 a couple of months ago, redone after 2 weeks and was 9.7. Saw consultant he said all 'felt' ok but arranged precautionary MRI. Results show a lesion that needs investigating which means a transperineal biopsy tomorrow. The comments in the MRI said no evidence in bones or lymph. Intermediate lesion possibility. Could this be cells that were missed 5 years ago?

Must say we are worried! Any thoughts and is it right that we will not get results until next appoint,ent on 4th November, it seems an awfully long wait?

User

Posted 05 Oct 2015 at 17:17

As my profile shows 1st biopsy all clear 2nd some 7 weeks after showed 4 cores out of 10 at Gleason 8 so on that basis yes it can be missed.

The timescale you gave for appointment is unfortunately not uncommon.

Good luck

Ray

User

Posted 05 Oct 2015 at 18:02

My first TRUS biopsy had zero cancer in all 10 cores , but indicators of pre-cancer ( ASAP / PINS ) in all . My template biopsy had 2 small cancers found out of 25 cores . My second TRUS only had 3 cores . But I ended up Gleason 9 T4 with spread to lymph nodes . And id had 2 MRI's and 1 CT scan . So yes it can be missed . Mine was way up at the back near the bladder
Good luck
Chris

User

Posted 05 Oct 2015 at 21:05

A biopsy can miss cancer, particularly the TRUSS one. The Transperineal one has a better chance of finding any cancer and also there is less chance of infection. I found standing or laying down no problem but I had to take care when sitting down to avoid some pain - tried to avoid pain killers as much as possible. I found it best to lower myself onto one cheek and and roll back into a slouch position. I adopted the reverse when getting up. I found if I sat upright it was rather painful. Things improved gradually over ten days or so. I had no blood in my urine but often men do experience it for a few days.

Edited by member 05 Oct 2015 at 21:10 | Reason: Not specified

Barry

User

Posted 05 Oct 2015 at 21:29

My husband was diagnosed end of 2012 Gleason 6 and has been on active surveillance since. In 2013 his trust biopsy was negative,spa stable for nearly 2 years. However this year psa rose to 10.9 then 13.5, mri was reassuring, but 3 weeks ago had a trans perineal biopsy,as you were told we are waiting for result in another week,so 4 weeks in all,long time! Unfortunately my husband had to have a catheter the night he came home after the biopsy as he went into retention which was quite traumatic for us both. The catheter was removed after 2 wks,but for last 2 night she has been up every hour to the toilet,he has no infection GPRS says,so bit worried as to why,plus we both very tired. Anyone had an experience like this?

User

Posted 05 Oct 2015 at 22:05

THank you all, knowing there is support and experience put there helps. I will post updates as and when 👍

User

Posted 05 Oct 2015 at 22:11

Yes the waiting is hard, keep us informed on things, it's good to talk 😌

User

Posted 06 Oct 2015 at 20:44

Well I didn't expect to be writing this today. After meeting with the surgeon, we declined the biopsies. He informed us that the MRI was inconclusive, the radiologist reported that it was prostatis and the surgeon admitted small area of concern would be difficult to target successfully and it could be missed. He said the hospital did not have the most up to date equipment and suggested we pay/use our health insurance to help pay for a better quality MRI - FUSION which would give more accurate results and then the biopsy done by the same hospital as the MRI would be only and precisely in the lesion/are of concern.

He apologise for not speaking to us in outpatients and recommending biopsy but due to the fact that previous biopsy was done by a different hospital /region and he didn't have the paperwork, he did not know if the area had previously been sampled. H says erratic PSA is probably caused by prostatis.

So, we will persue alternative MRI and GP will treat prostatis and we will take alternative therapy to reduce inflammation too.

I will post what happens should anyone be interested

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