Hello everyone. This seems like a wonderful site. My husband has always gone for checkups and it always seemed "so they said" within normal limits. Than this past year his PSA went from 3.6-7.13 within a six month period. His DRE seemed normal but the biopsy showed 8 out of 12 positive cores of adenocarcinoma and a gleason score of 4+3 , and the scan showed a pelvic bone met (Iliac bone) so how did all this occur in a six month period????? This is freaking me out as I don't know if this was there awhile "simmering" but never showed up in the PSA or if within six months it could have grown and headed outside the prostate?? Anyone have this experience? Also he is now on lupron shot, casodex and a bone strengthening shot. How did this come out of nowhere? He is 65 yrs young and always was in great health. Help!