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Can exercise cure Prostate Cancer!

User
Posted 06 Jan 2016 at 10:58

I glanced at Sky News this morning and I must admit I was really annoyed! A Phd individual seemed to be suggesting that it is maybe our fault that we developed Prostate Cancer because we did not exercise enough, or are not exercising enough after we are diagnosed? He seemed to be floating the idea that exercise might be one of the answers to stop people developing the problem further and to possibly avoid treatment for it in the future?


I was diagnosed with Prostate Cancer in December 2014 and had my Prostate removed in April 2015. I have maintained good fitness for most of my life. I am not overweight, I do not eat meat, do not smoke or take drugs, never have biscuits, sugar or salt in the house and until my Prostate operation I ran between 3-5 miles a day, mostly about 6 days a week. I hope to get back to running from February. On top of that I hike long distance as a hobby and I'm often away for up to 12 weeks out of 52 slogging up and down mountainous. My only 'vice' is that I enjoy a pint or two!


What so annoys me is we have been told that all sorts of things are bad for us (wine, butter, sugar etc comes to mind) and then we are told that many of these items are actually good for us! The viewing public gets these conflicting messages all of the time and I have reached the point where I just view these medical slots as rubbish and am cynical enough to believe that most of the advice is from people who want to be on the telly, or they see it as a means to advertise themselves as they climb the slippery slope to being top dog in their chosen career.


Or is it, I ask myself, is it just the government of the day trying to blame us and other medical groups for becoming ill in the first place, i.e. its our fault! As this government makes more and more of a hash at running and funding the NHS it it would seem to me to be rather clever to divert attention away from them and from Mr. Hunt in particular and blame us, the public for the mess that they have created in the first place. In effect maybe the suggestion is that the NHS would work fantastically well if it wasn't for all those bloody pleb patients out there who want to have treatment for their self inflicted illnesses!


Why are these so called 'experts' allowed out of the woodwork to confuse us via national television and other media outlets. I suppose I would answer its because even illness, war, famine and so on are now just part of the entertainment industry. If you have competing 24 hour news channels you have to fill the time slots somehow.


Sorry folks but I needed a rant today. I'm now going for a muddy hike in the woods!

User
Posted 07 Jan 2016 at 12:59

interesting Lyn,


No vasectomy.


Not a engineer


Cant remember the last time i rode a bike.


Never been on a motor bike.


And prior to HT, yes i was a man http://community.prostatecanceruk.org/editors/tiny_mce/plugins/emoticons/img/smiley-laughing.gif

Don't deny the diagnosis; try to defy the verdict
User
Posted 08 Jan 2016 at 12:13

I think the issue is not whether research is useful or not, it is the manner in which it is conducted that is the problem. The trial is a pre-evaluation of whether exercise can help to reduce the rate of development of prostate cancer and is another example of a "scatter gun" approach to finding factors that may be of help. I read the description of the trial on the Cancer Research website, and was a bit worried. 50 men will be recruited, of whom 25 will be put on a supervised exercise programme, and 25 on a specified, but not supervised programme. Men aged between 50 and (I think) 70 will be included. That in itself is a pretty small sample size, and does not mention consistency in other factors that could influence prostate cancer growth - how aggressive the cancer is, genetic background, ethnicity, height, weight, starting level of fitness, diet (and the recently reported factor of the regularity of ejaculation) etc etc. And on top of this, there is no mention of a control group who just get on with life.

Personally, I have had experience of the effects of two of these "scatter gun" approaches. One is the well-known pelvic floor exercise to reduce incontinence mantra. If men do pelvic floor exercises and their incontinence after prostate removal is reduced or goes away, then the PFEs are cited as the reason, but would they have improved without them? Who can possibly know? For me, PFEs did not work, or have any noticeable effect at all, therefore, using the same logic, they are at best an irrelevance.

The second experience concerned testosterone replacement therapy. In 2014, I had a truly miserable time with almost continuous colds, coughs and chest infections, and eventually was diagnosed as having testosterone levels very close to zero. (and no, I have never been on hormone therapy). Despite having five years of unmeasurable PSA, I had to have a massive argument with the endocrinology specialists before being allowed to have TRT. Their assertion that TRT could bump up PSA and possibly restart prostate cancer elsewhere in my body was based on research that was about 60 years out of date, with a minimal sample size, and they took no notice of 15 years worth of subsequent published research debunking the relationship between testosterone and the resurgence of prostate cancer after prostate removal.

Concentration of attention on researching the fundamental clinical causes of prostate, and other cancers will, eventually, yield firm results, and from these results, other factors, even such as exercise regimes, may be identified as contributing factors. My problem is with research done the other way round and being treated as definitive.

Tony
TURP then LRP in 2009/2010. Lots of leakage but PSA < 0.1 AMS-800 Artificial Sphincter activated 2015.
User
Posted 06 Jan 2016 at 19:09

I did try to explain what the research was about this morning but it appears there is no trust here. So read the research here:

http://www.cancerresearchuk.org/about-cancer/find-a-clinical-trial/a-trial-of-exercise-as-treatment-for-men-with-prostate-cancer-pantera

User
Posted 06 Jan 2016 at 21:34

Hi Guys,


A few random thoughts that occur to me are as follows:


We often talk of PCa as a 'disease', perhaps implying that it is something alien to our bodies which we catch or develop?


However the NHS statistics, from autopsies, reveal that as we get older we pretty much all get cancer, 60% of men in their 60's have some detectable prostate cancer, and the older we get the more likely that is.


So should we perhaps consider cancer as a purely natural side effect of aging?


This of course causes us pschological problems, because we are not really at ease with the concept that we are all going to get old and die, but before we do various bits of our bodies are going to deteriorate.  So we try and rationalise this, believing if we don't let bits of us deteriorate we won't die?


On the subject of research, is all medical research conducted with equal vigour, and is some of it flawed?


Take for example my mother, she died last year aged 88 after a pretty good life.  Her final years were a slow spiral of decline, an irregular heart beat caused her to slowly become senile, atrial fibrilation causing vascular dementia, 2 years before she died she sufferred a minor stroke, a lacunar infarct, it put her briefly in hospital but wasn't a major issue, 12 months later she sufferred a big profound stroke, the sort that literally knocked her off her feet, she never walked again, it destroyed her memory and put her in a nursing home for the rest of her life.


When she died, a doctor who didn't know her, thumbed through her notes and recorded on her death certificate the lacunar infarct as a contributory factor to her death, there was no mention of the major stroke!


I don't blame that doctor, in a busy day with lots of living patients to care for, there is not time to read copious medical notes before signing off a death certificate.


However that raises the question of how valid is any medical research which takes any notice of what is recorded as cause of death?   


So to return to the main point, who knows what causes cancer, and on what research is that knowledge based?


:)


Dave

Edited by member 06 Jan 2016 at 21:36  | Reason: Not specified

User
Posted 06 Jan 2016 at 22:58
Originally Posted by: Online Community Member

Just a quickie to Mo,

I had a vasectomy in the early 70's and then a reversal op in 1978, am I at risk, was I at risk? I must have been as I have PCa.

Surely there is no research that suggests this, is there?

Cheers Chris/Woody

Life seems different upside down, take another viewpoint



Chris

sorry I didn't mean to alarm you or anyone for that matter, it was just another tiny piece of research based on statistics. Not post mortem ones as Dave has since mentioned (and yes I have to agree they often miss out some pretty key historic illnesses.)

If you think about it the increase in the number of men having a vasectomy in the era where there was so much doubt about the safety of the pill and prior to the plethoria of birth control stuff there is available now, then as PCa has become much more frequently diagnosed, there is a much higher statistical likelihood of a vasectomy having also been performed.

I was just trying to highlight that any possible link to activity from or on the prostate seems to be a fair research target. It is one of the reasons statistics can be a politicians best friend, in some cases they can be turned any which way you like.

The number of vasectomies being performed today has rapidly declined and is way lower now (60% lower) than 10 years ago even, so if that theory held good then relativley speaking by now we should have seen a decline in PCa diagnosis not an increase.
so in my humble opinion, the vasectomy or subsequent reversal quite probably had no bearing on your current situation.

Just to add the change in the op in the 70s was just a procedural thing with the advent of new technology.

sorry if I caused you any concern that was never my intention
xx
Mo


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User
Posted 06 Jan 2016 at 11:04

Rant away GWM


Perhaps men could take up riding bikes for long distances. It would keep you healthy eh.


Oh hang on, isn't there some doubt as to whether that causes testicular/prostate cancer ?


(or have I misunderstood that?)

Edited by member 06 Jan 2016 at 11:06  | Reason: Not specified

We can't control the winds - but we can adjust our sails
User
Posted 06 Jan 2016 at 11:22

I totally agree with your comments GWM,


Lack of regular exercise certainly had nothing to do with my PCa diagnosis.....

In fact, on the contrary!
It was only because I visited my GP for an ongoing knee problem that was restricting my exercise that my PCa was discovered in the first place! ( check out my profile for details )


No thanks to my GP I might add as he 'talked me out' of having a PSA test 2 years previously....

Luther


User
Posted 06 Jan 2016 at 12:34

I am sorry to disagree here but the research is not a PhD study and is being conducted as quite a big study known as Pandera trial and is funded by Cancer Research UK. It is in its early stages but it is focused on those with localised early stage cancer to see if exercise can reduce the need to move onto surgery, RT etc. So I guess for those in watchful waiting or active surveillance. Early results have been encouraging and the media has picked up in this but this is a detailed funded study and not about getting an academic career advancement. It is such research that has brought us early chemo, abiterterone, enzalutimide and radium 223. That research has given those of us with advanced cancer some hope for prolonged life, it is good to see some research focused on early stage PCa so we should await its finding with interest not scepticism. This is not about what you did prior to a diagnosis as implied in the post.

User
Posted 06 Jan 2016 at 14:19
GWM

initial reaction for a previously very fit and healthy man may well be idignance. I am sure if I had seen the TV program and heard it in the same context as you I would have wanted to let steam off. I did look online at some of the Pandera study though and it really is trying to figure out if our lifestyle may be something that contributes to illness. Similar studies over the years have proved pretty conclusively the things that Harm us in our lifestyle such as smoking, excessive consumption of alcohol, being overweight or obese and lack of exercise.
Of course most of those were aimed at other cancers. Indeed one more recent study linked infrequent ejaculation with testicular or prosate cancers and possibly even vasectomies performed prior to the mid 70s when the procedure was changed.

Now some of the focus is moving towards things we should do rather than avoid.

The academic and medical world are working for us to try and give us information that will help us make decisions based on their findings. As with many other things in life we just have to take on board what we believe will help or work for us.

That said I do understand you letting off steam a bit

all the best
xx
Mo
User
Posted 06 Jan 2016 at 15:20

Hi,


I have PCa, just finished 2 years Zoladex after Bracchy. Can only do about 4 hours clear thought a day because of extreme fatigue, and joint pain (like now). But that is not what I wanted to talk about right now. It is just to share the total agreement about hating the "blame the victim" syndrome. I have done a bit of digging into it I don't want to be political, but some research I have read says that it is associated with very right wing philosophies, going back to at least to Herbert Spencer, and still alive in the USA. 


Otto

User
Posted 06 Jan 2016 at 15:45

I just basically take all this talk with a pinch of salt. And studies. Butter is bad , no it's good , no it's bad etc. Are people actually going to listen after millions of pounds worth of research. Are they going to jump out of bed on a Sunday for a walk , rather than a boozy Saturday night and a fry up in the morning?? Some people may , but millions avoid the advice on smoking , drinking , sugar intake etc. I find it all a bit boring , like the friend who is banging on and on at me to eat 3 trees worth of Broccoli each day as it will "definitely" cure my cancer.
It can't be beaten yet , and I totally approve of research , but I think it goes a lot deeper than diet or exercise to be honest.
Chris

User
Posted 06 Jan 2016 at 16:09
What a load of codswollop
I dont smoke or drink have run marathons for the past 20years
Training weeks of 80miles a week
But still have metastatic cancer
Must be i wasnt doing enough or it was the wrong excersise
run long and prosper
'pooh how do you spell love'
'piglet you dont spell love -you just feel it'
User
Posted 06 Jan 2016 at 16:30

Calm down boys .... or read the actual research overview! Get angry with the media for sloppy reporting, not the cancer researchers who are trying to get better outcomes for people like us by testing out whether exercise can help an early-diagnosed patient to avoid radical treatment and its attendant side effects.

GWF, who knows - they might one day be able to prove that many men don't actually need surgery and that is the kind of progress I would wish for my sons / grandsons/great-grandsons. Clearly does not apply to men with advanced PCa.

Poor Cancer Research UK to end up with poor quality sensationalist media coverage.

"Life can only be understood backwards; but it must be lived forwards." Soren Kierkegaard
User
Posted 06 Jan 2016 at 16:47
I was surprised when I saw on the BBC web this am a chap on a bike. My initial thought was that following research for causes of PC several times being on a saddle was one of them.
I too keep fit. Walk everyday. Garden. Play tennis/ badminton. Exercise classes. And this for ever.
But I accept the general views shown here. And it is for research.
User
Posted 06 Jan 2016 at 16:56

I saw the news item on BBC Breakfast this morning...

Although I was half asleep, the impression I got from the report was that exercise may help men from getting  PCa in the first place?

As Lyn says, maybe it was sloppy reporting that made us all irate?

Or maybe I simply misunderstood the report!.... http://community.prostatecanceruk.org/editors/tiny_mce/plugins/emoticons/img/smiley-smile.gif

Luther 

Edited by member 06 Jan 2016 at 17:01  | Reason: Not specified

User
Posted 06 Jan 2016 at 19:09

I did try to explain what the research was about this morning but it appears there is no trust here. So read the research here:

http://www.cancerresearchuk.org/about-cancer/find-a-clinical-trial/a-trial-of-exercise-as-treatment-for-men-with-prostate-cancer-pantera

User
Posted 06 Jan 2016 at 20:43
Originally Posted by: Online Community Member
I was surprised when I saw on the BBC web this am a chap on a bike. My initial thought was that following research for causes of PC several times being on a saddle was one of them.
I too keep fit. Walk everyday. Garden. Play tennis/ badminton. Exercise classes. And this for ever.
But I accept the general views shown here. And it is for research.


Sorry Surr, there is no evidence that I am aware of that cycling causes PCa. It could be that you have confused two other things:-
a) men who are competitive cyclists tend to produce a higher PSA but generally are not at any increased risk of getting cancer. The recommendation to urologists as a result of the research was that if a man presents with high PSA but is a keen cyclist, some thought should be given to whether an unnecessary biopsy can be avoided

b) many uros will advise not to cycle for a period of time after nerve-sparing surgery - this is to give the nerve bundles the best chance of repairing, thus reducing the risk of permanent ED

I don't think I have ever seen research to suggest that men should avoid cycling when on AS or between diagnosis and treatment, etc

"Life can only be understood backwards; but it must be lived forwards." Soren Kierkegaard
User
Posted 06 Jan 2016 at 21:12

Just a quickie to Mo,

I had a vasectomy in the early 70's and then a reversal op in 1978, am I at risk, was I at risk? I must have been as I have PCa.

Surely there is no research that suggests this, is there?

Cheers Chris/Woody

Life seems different upside down, take another viewpoint

User
Posted 06 Jan 2016 at 21:34

Hi Guys,


A few random thoughts that occur to me are as follows:


We often talk of PCa as a 'disease', perhaps implying that it is something alien to our bodies which we catch or develop?


However the NHS statistics, from autopsies, reveal that as we get older we pretty much all get cancer, 60% of men in their 60's have some detectable prostate cancer, and the older we get the more likely that is.


So should we perhaps consider cancer as a purely natural side effect of aging?


This of course causes us pschological problems, because we are not really at ease with the concept that we are all going to get old and die, but before we do various bits of our bodies are going to deteriorate.  So we try and rationalise this, believing if we don't let bits of us deteriorate we won't die?


On the subject of research, is all medical research conducted with equal vigour, and is some of it flawed?


Take for example my mother, she died last year aged 88 after a pretty good life.  Her final years were a slow spiral of decline, an irregular heart beat caused her to slowly become senile, atrial fibrilation causing vascular dementia, 2 years before she died she sufferred a minor stroke, a lacunar infarct, it put her briefly in hospital but wasn't a major issue, 12 months later she sufferred a big profound stroke, the sort that literally knocked her off her feet, she never walked again, it destroyed her memory and put her in a nursing home for the rest of her life.


When she died, a doctor who didn't know her, thumbed through her notes and recorded on her death certificate the lacunar infarct as a contributory factor to her death, there was no mention of the major stroke!


I don't blame that doctor, in a busy day with lots of living patients to care for, there is not time to read copious medical notes before signing off a death certificate.


However that raises the question of how valid is any medical research which takes any notice of what is recorded as cause of death?   


So to return to the main point, who knows what causes cancer, and on what research is that knowledge based?


:)


Dave

Edited by member 06 Jan 2016 at 21:36  | Reason: Not specified

User
Posted 06 Jan 2016 at 22:58
Originally Posted by: Online Community Member

Just a quickie to Mo,

I had a vasectomy in the early 70's and then a reversal op in 1978, am I at risk, was I at risk? I must have been as I have PCa.

Surely there is no research that suggests this, is there?

Cheers Chris/Woody

Life seems different upside down, take another viewpoint



Chris

sorry I didn't mean to alarm you or anyone for that matter, it was just another tiny piece of research based on statistics. Not post mortem ones as Dave has since mentioned (and yes I have to agree they often miss out some pretty key historic illnesses.)

If you think about it the increase in the number of men having a vasectomy in the era where there was so much doubt about the safety of the pill and prior to the plethoria of birth control stuff there is available now, then as PCa has become much more frequently diagnosed, there is a much higher statistical likelihood of a vasectomy having also been performed.

I was just trying to highlight that any possible link to activity from or on the prostate seems to be a fair research target. It is one of the reasons statistics can be a politicians best friend, in some cases they can be turned any which way you like.

The number of vasectomies being performed today has rapidly declined and is way lower now (60% lower) than 10 years ago even, so if that theory held good then relativley speaking by now we should have seen a decline in PCa diagnosis not an increase.
so in my humble opinion, the vasectomy or subsequent reversal quite probably had no bearing on your current situation.

Just to add the change in the op in the 70s was just a procedural thing with the advent of new technology.

sorry if I caused you any concern that was never my intention
xx
Mo


User
Posted 07 Jan 2016 at 01:58

Having said that, when we did some (not very scientific) quantative research on a thread here one day (when a few of us were bored a few years ago) the common factors were really interesting:
- a large proportion had had a vasectomy
- quite a lot had been engineers or worked with oils / chemicals
- loads were keen cyclists
- quite a number had motorbikes
- almost all were men :-)

"Life can only be understood backwards; but it must be lived forwards." Soren Kierkegaard
User
Posted 07 Jan 2016 at 12:33
Thanks Lyn
we can always rely on you to put it into perspective !
funnily enough though Diabetes didn't get mentioned ..poor Mick on those statistics FFS good job I didn't see that info at the time (insert a sort of smiley face) after all I stil retain my sense of humour I think.
Mody Diabetic, had a vasectomy in 1975, was a pilot and aircraft /car/motorbike mechanic extraoridinaire, was a very keen cyclist and rode a motorbike. ...oh and he was definitely a male.


xx
Mo
User
Posted 07 Jan 2016 at 12:59

interesting Lyn,


No vasectomy.


Not a engineer


Cant remember the last time i rode a bike.


Never been on a motor bike.


And prior to HT, yes i was a man http://community.prostatecanceruk.org/editors/tiny_mce/plugins/emoticons/img/smiley-laughing.gif

Don't deny the diagnosis; try to defy the verdict
User
Posted 07 Jan 2016 at 13:25

This shows the difficult of interpreting research, it is always hedged with many caveats.

I had a vasectomy circa 1983 as a direct result of testicualr cancer, never been anywhere need an engineer, scared of motor bikes and only cycled as a child and after four years of hormone therapy not quite sure on the man front.

What can help us in understanding the benefits of research?

Size of study, generally the larger the better
Whether there is a control group, randomised control trials regarded as the gold standard
How research relates to other research in same field
Funded by reputable organisations e.g, cancer research UK
Ignore media representations and go to the actual research
International comparisons which confirm findings
Research methodology itself (though this is very technical and difficult to understand unless you a a researcher yourself)
The researchers themselves, who are they what are their credentials in research

It is complicated. We are human subjects and even with medical research ethics and morals can intervene.

Edited by member 07 Jan 2016 at 13:27  | Reason: Not specified

 
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