I was diagnosed in February with locally advanced PC (it has gone to the seminal vessels but not lymph nodes). That was two days after my dad had died of it and I had no symptoms apart from some tiredness, certainly no bone pain. PSA 6.5 and Gleeson 9. A subsequent radio isotope scan showed a dark patch on one rib, which though the radiologist felt was mets the consultant said it was rare to see an isolated high uptake like that and asked if I had had broken ribs at some point - yes, since I had ridden a motorbike and had several accidents when younger, but couldn't remember which ribs were broken. A further MRI seemed to indicate there was possibly some kind of bone injury but a further ct scan said they could not see this and diagnosed probably mets. So without any firm conclusion, we have asked for a bone biopsy and are awaiting a decision on this before either radiotherapy or chemo. They told us at one point they had taken a view that it was not mets so we just don't know where we are and it is like a roller coaster from hell. We are pushing for a diffinitive diagnosis and thinking of taking a second opinion from another consultant out of area. Has anyone else had this kind of issue?