Using statins with ADT?

Hi Zet

Seen this study and others before. Maybe I missed it but.... did it take into account the PC patients Cholesterol+Testosterone levels BEFORE the study?

Correct if i'm wrong but the reason why they were taking statins to begin with was because they had high Cholesterol levels  ie; Cholesterol=Testosterone? That is one of the reasons why we should stay away from egg yolks and high cholesterol foods perhaps?

VEGANS have Lower Cholesterol levels than BOTH vegetarians and meat eaters....and guess what: "Scientists at Loma Linda University in California, USA looked at the eating patterns of over 26,000 men.   The results showed that men who were identified as following a vegan diet had a 35% reduced risk of prostate cancer."

This of course could have a MULTITUDE of reasons.... 

Diabetes (and ADT) is not something that worries me too much....since I think Diabetes can be managed (I think) by the individual to a large extent.

What worries me about LONG term ADT is this:

"Men taking androgen deprivation therapy (ADT) for prostate cancer were almost twice as likely to be diagnosed with Alzheimer’s disease in the years that followed than those who didn’t undergo the therapy, an analysis of medical records from two large hospital systems by Penn Medicine and Stanford University researchers has shown. Men with the longest durations of ADT were even more likely to be diagnosed with Alzheimer’s disease." 

Bill

Edited by member 09 Jun 2016 at 07:19  | Reason: Not specified

Hi Andrew

"Cholesterol=Testosterone" - No! ;-)

Yes! ;-( I'm afraid so......

"Cholesterol also can contribute to the development of anti-hormone resistance because cholesterol is converted into hormones in tumor cells; therefore, these cholesterol-forming pathways are attractive therapeutic targets for the treatment of prostate cancer."

There is quite a bit out there but this is a good one....

https://www.sciencedaily.com/releases/2016/04/160414170034.htm

This here is a good start (Cholesterol=Testosterone) :

https://en.wikipedia.org/wiki/Leydig_cell

As far as Alzheimers here is a good start (very recent study)....The  reason why it worries me is that WE KNOW that ADT may affect our bones and muscles...but we can change our diets or have additional treatment for these.  

Alzheimers however is a death sentence...What do we do? How can we prevent it? What is the cure?

Heck....I have Alzheimers family history! 

http://www.uphs.upenn.edu/news/News_Releases/2015/12/nead/

Late Editing:

ONCE again I find myself looking at Japan for dietary guidance (Japan should be the benchmark for Prostate/Breast Cancer Survival Strategies in my view).

Unfortunately Japan is adopting some very nasty Western dietary habits...consequently Prostate/Breast cancer rates are rising....but NOWHERE near the current Western levels.

Nevertheless......as far as Alzheimer/Dementia Death rates (per 100k pop):

USA...........45.58

UK.............24.35

Germany....13.39

Japan.........4.23

Interesting to note....Just like prostate cancer...

"Alzheimer’s rates of Japanese-Americans living in the U.S. are closer to that of Americans than to Japanese. When people move from their homeland to the United States, Alzheimer’s rates can increase dramatically..."

Edited by member 09 Jun 2016 at 13:26  | Reason: Not specified