I haven't posted for a while because my 55 year old brother was having treatment for his locally advanced PCa. His PSA on diagnosis in April 2015 was 172 (yes, high!), gleason 7 but no signs of spread other than locally. We were devastated at the time and preparing ourselves for the worst. He's just finished radiotherapy and before that had chemo (he had to stop after 5 cycles because of side-effects) and of course continues on HT. He had some side-effects from his treatment including fatigue and some peripheral neuropathy but these are improving. He has increased urination (between 3-5 times a night) but has been told he'll have to live with this and says he can accept it.
We had a post-treatment meeting with his oncologist earlier in the week and she reported a PSA of 0.02, told him she was very happy with how he'd responded to treatment and now only wants to see him once every 6 months. He'll continue on HT but can come off it after 3 years if his PSA stays down. She was even talking in terms of him being possibly cured, though he'll have to live with being monitored and be prepared for possible PSA rises in future. But considering that on diagnosis he was given between 2-10 years and told it was incurable, we're all incredibly pleased.
I would like to think that his story so far will offer some hope to those with a similar diagnosis and I can't speak highly enough of our amazing NHS.