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Link between PCa and bowel cancer

Posted 12 Jan 2018 at 07:46
Hi not sure if this has been covered before. But does anyone know if there is any link between PCa and bowel cancer. Also is there any genetic link.

I am asking as my brother was on Active surveillance for PCa and at his MRI they discovered a mass in his colon. He had surgery this week to remove a malignant tumour. Hence my questions

Another thought that had crossed my mind since my brothers dx is should men who have had RT be screened at some periodic interval as the RT can increase the risk of secondary cancer

Posted 12 Jan 2018 at 13:04
They are two quite separate diseases.
Though it's theoretically possible for PCa to metastasise to the bowel (and vice versa), I don't think that's at all common.
The national bowl screening programme doesn't exclude men with prostate cancer, though it only covers a certain age range.
Secondary cancer following RT is also very uncommon, Though we all need to be aware of the risk, especially if we get altered bowel habits or rectal bleeding.

Edited by member 12 Jan 2018 at 13:07  | Reason: Not specified

-- Andrew --
"I intend to live forever, or die trying" - Groucho Marx
Posted 12 Jan 2018 at 19:19

Andrew,. The incidence of secondary cancers following RT is not "very uncommon". There is a great reluctance on the part of oncologists to accept that subsequent bladder cancer (which both my late brother and I got within five years if having RT) and bowel cancer is related to poorly aimed RT. I am very doubtful about the collection of statistics on this, therefore.

I'm sure that modern methods are a great improvement on what was done ten years or more ago, but all who had RT in those early days should be watchful for the signs suggesting a problem.


Posted 12 Jan 2018 at 19:33
Depends how you define uncommon.

Most studies put it at 2-5%, and, as you say, things have probably improved as RT techniques have improved. Such studies are necessarily retrospective.

From what you say, you and your brother have not had a 'typical' experience, and that's awful. And, of course, the same thing could yet happen to me. But individual experience does not invalidate studies of many thousands of men - who may be luckier than we are.

interesting article on the subject!

Edited by member 12 Jan 2018 at 19:37  | Reason: Not specified

-- Andrew --
"I intend to live forever, or die trying" - Groucho Marx
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