Hello all (- This is my first post anywhere, ever, so please excuse any gaffes !)
Has anyone experience of Abiraterone plus Prednisone side effects, treating advanced metastatic prostate cancer, please? Or those of Stereotactic Body Radiotherapy (SBRT) on bone metastases ? (- see later)
I have just been offered the Abiraterone treatment, as my Prostap treatment is failing to work after 3 years - PSA is now rising steadily from virtually zero , currently 4.
I currently feel well and pretty normal (I'm in my early 70's), and I am still able to be active, so I'm reluctant to sacrfice this to treatment side-effects if the only gain might be a couple of months more survival. ( - Although my Oncologist reckons he has at least one patient still going strong on this regime after 5 years)
I was diagnosed ( no pre-symptoms) 3 years ago, and then staged G6+9 T3 N1 M0. I was given a course of Radiotherapy combined with the Prostap, ( surgery was not offered as the cancer had broken the Prostate capsule, and there were indications in the pre-sacral nodes). I've been fine apart from the usual Prostate effects (flushes, no libido, weight gain, less energy).
Ongoing scans suggest mets in or near the spine or ribs, along with the rising PSA.
I have also been offered access to one of two Trials as well as the "Standard" treatment above - one with Ipatersertib + Abiraterone + Prednisone, and one which involves intensive stereotactic radiation (SBRT) of the mets ("CORE" Study), again along with the Abiraterone +Prednisone .
Anyone with experience of any of these treatments, please?
Any information or encouragement much appreciated !