I am sorry for being disconnected from the forum and somehow I didn't receive any notifications of any replies. It is now August 2018 and my father was receiving an injection of zoladex every 28 days so a total of 8 injections have been given to him .
On the 6th month now when the PSA was done, the PSA has increased to 10.
Initially on the 3rd month the PSA was about 0.28.
In between I decided to check myself the PSA which came to 4. I also noticed that on the 3rd month when testosterone readings were taken they were normal as in non castration. Which meant that maybe the combined therapy wasn't reducing the testosterone levels.
I redid them for him on the 5th month and they were then zero i.e. castrate levels. Don't know why in between the testosterone readings were normal . The oncologist also didnt answer this query for me.
What happened in between was that initially there was a reduction in almost all the symptoms but now after 3rd month the urinary frequency has increased a bit. This was noticed by my father who expressed it. He also seems to have muscles aches and pains on an off. I guess it might be related to the injections.
The next appointment with the oncologist is to be on the 29th of August, but as I saw the PSA of 10 I want to go to the Oncologist and discuss what is next in line for the treatment for my dad.
As far as I have read about Prostate cancer treatment, if combination treatment with zoladex and once daily of casodex 50mg tablets is given, then if there is a rise in PSA the doctors tend to stop the once daily tablets and then a drop in PSA would be noticed. I don't know if that would be the case here but the oncologist would be the judge of what treatment is next in line.
Similarly the Oncologist had expressed that he might go for Radiotherapy if the PSA drops to below 1. Which hasn't happened. So I dont know if radiotherapy might be considered or not.
Docetaxel is available but it was not started. My father is 70 years of age.
LynEyre thank you so much for the reply. I guess you are right about that. Though when I am reading there are multitude of various new treatments like immunotherapy and HIFU (High intensity focused ultrasound) which are currently being done in some hospitals in the UK.
Similarly Firmagon is being offered as the first line instead of Zoladex injections in UK. It is not available here. Mainly the mainstay treatments here are zoladex and casodex.