I'm interested in conversations about and I want to talk about
Know exactly what you want?
Show search



Zoladex or Lupron

Posted 17 Jun 2018 at 18:00

I know from the Stampede trial that upfront chemo along with Hormone Therapy can extend the life of men, but how does the oncologist decide which Hormone therapy to use and which may be better alongside chemo.  I see a lot of people are given Zoladex or Lupron (Prostap) but is one proven to better than the other ?

Posted 17 Jun 2018 at 18:59
I think this is all horrendous Emma.
Am I at a disadvantage because I haven't been offered upfront chemo?
I believe I am on Prostap 12 week injections because it is cheaper (I was private care when this was decided). Is this another risk?
What are the criteria to go on Stampede trial?
I haven't seen my specialist for well over 2 months!!! That's why you innocent people get all my paranoic postage!
Richard x
Posted 17 Jun 2018 at 20:28

Hi Richard, 


From what I know the STAMPEDE trial aims to provide evidence as to what is the best way of treating men with newly diagnosed advanced prostate cancer.  I believe you are locally advanced ?  So I don't think this would have put you at a disadvantage.  You can see more Q & A on the PCUK website https://prostatecanceruk.org/about-us/news-and-views/2015/5/your-questions-answered-on-stampede .

Again in my personal opinion that the fact that Prostap is cheaper ( I too was told this is cheaper than Zoladex) shouldn't matter, I have been told by 2 different specialist nurses that these do the same thing.  Although again my personal view differs.

You can look at the Stampede trial, criteria etc on cancer research website, this is continually evolving an d trying different things  http://www.cancerresearchuk.org/about-cancer/find-a-clinical-trial/a-trial-looking-at-hormone-therapy-with-zoledronic-acid-docetaxel-or-celecoxib-for-prostate-cancer


Hope this is of some use Emma x


Edited by member 17 Jun 2018 at 20:29  | Reason: Not specified

Forum Jump  
©2019 Prostate Cancer UK