Diagnosed with Locally Advanced PCa early June (T3bN1M0 (initial now M1) Gleeson 9 5+4 100% single core Initial PSA 73). Signed up for STAMPEDE Trial and my treatment started with HT (Prostrap) 20th June and Chemo (Docetaxal) started on 3rd July this year. Final PSA result just prior to 1st chemo was 108.
This is what they call up front treatment and is meant to be very benificial as opposed to waiting for the PCa to progress before reverting to chemo.
After 4 weeks PSA down to 9.9 and after 7 weeks reading was 3.9! I am tolerating the Docetaxal very well after 3 sessions, some mild indigestion initially then mouth feels metallic and taste goes a bit funny for a few days. After that the Steriod pills kick in and I seem to have an abundance of energy. Not felt any adverse reaction to the Prostap injection and just moved to 12 week ones.
Not able to have RT as PCa has spread to lymph nodes well outside the pelvic region and my PET scan found a very small bone metastases in the pelvic bone.
So in summary, HT seems to be working well and have been told I will be on this for my lifetime. Have been told I will have another scan after my 6 chemo session (mid October) to assess what has happened to the affected lymph nodes and bones. Wish this wasn't so long but they insist that the chemo treatment run it course.
If anyone who reads this and is in a similar position to mine when you have been diagnosed go for the up front treatment.