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Just joined, looking for some advice

User
Posted 20 Aug 2018 at 21:19

Hello,

I was diagnosed with T1c tumour in April. Gleason score 3+3. I have been advised by my specialist to have a template biopsy, as yet no appt. date set. 

Anyone had this procedure?

Will I still be given an option of a radical prostatectomy even if it’s results show the same as my previous biopsy?

Im taking some comfort from the fact that my specialist doesn’t appear to be ‘rushing’ but am still concerned that there are cancer cells in my prostate!!

Thank you

User
Posted 21 Aug 2018 at 12:30

Originally Posted by: Online Community Member

Thanks, not sure which route to take. Was given a radical prostatectomy option when first diagnosed in April, but now wondering why I'm having a template biopsy. 

I have been having regular PSA Tests for last 4 years, every 6 mths, lately every 3.

Can't see what active surveillance is going to achieve now when cancer is confirmed ??

Appreciate your response

Alistair

Active surveillance is a perfectly proper option, it might be that no intervention is required during your lifetime. Many of us have had, or still have, cancer cells, but they grow so slowly that old age finishes us off before it gets to be a problem.

Why go through a nasty surgery and potential incontinence just in case.? PC is different from most other cancers which can spread rapidly and before you know it, it's too late. It's so slow that many GPs won't investigate "just in case"

User
Posted 21 Aug 2018 at 07:52
Hello alpark and welcome

Don't have the expertise you need but with a 3+3 I can understand that the specialist is a bit laid back about it all.

Were you opting for the surgery or are you thinking of other treatment or even Active Surveillance?

We can't control the winds - but we can adjust our sails
User
Posted 21 Aug 2018 at 08:36
alpark, an awful lot of us here have had a template biopsy, and it's absolutely nothing to worry about. It's done under general anaesthetic as a day procedure. You'll have a spectacular bruise on your perineum (the skin between your testicles and back passage) and it'll be sore to sit down for a day or two, but that's it. You'll probably pass a bit of blood when you pee for a couple of weeks after. You'll get the results a couple of weeks later.

Don't worry about it.

Chris

User
Posted 21 Aug 2018 at 23:49

Originally Posted by: Online Community Member

Fresh

That's the dilemma I'm facing.

I can only think that my particular specialist prefers this course of action.

It's something I will discuss with him, but I do understand from previous responses to me that they can find different grades of cancer cell deeper inside the prostate. That may alter my treatment plan. 

I'll keep the thread updated in due course

Thanks for your message,appreciated

 

 

Three likely possibilities come to mind:-

a) consultant wants to be sure it is a G6 before recommending AS to you 

b) your PSA is higher than s/he would have expected for a low level cancer diagnosis

c) one or more of the cores showed a high % cancer OR in one or more cores, the cancerous cells were close to the edge

"Life can only be understood backwards; but it must be lived forwards." Soren Kierkegaard

User
Posted 22 Aug 2018 at 08:00

Originally Posted by: Online Community Member

Why do they need the second biopsy?

Fresh

Because in a TRUS biopsy they take between 6 and 12 core samples, and in my template biopsy they took 42. I had a perineum like a pin-cushion! But no pain apart from the first two post-op wees where the urethral catheter had been fitted and removed.

Thus it’s much more accurate and if he’s lucky enough to go on Active Surveillance, i.e. do nothing, carry on living as normal and just have quarterly blood tests, a template biopsy will enlighten him and his clinicians as to whether anything more sinister is lurking outside of those 6 to 12 samples, and whether AS is appropriate. Fingers crossed 🤞 

Cheers, John

Edited by member 22 Aug 2018 at 10:03  | Reason: Not specified

User
Posted 23 Aug 2018 at 09:08

Clare,

I will check the book out and thanks for your comments

Hope OH is progressing well

Alistair

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User
Posted 21 Aug 2018 at 07:52
Hello alpark and welcome

Don't have the expertise you need but with a 3+3 I can understand that the specialist is a bit laid back about it all.

Were you opting for the surgery or are you thinking of other treatment or even Active Surveillance?

We can't control the winds - but we can adjust our sails
User
Posted 21 Aug 2018 at 08:36
alpark, an awful lot of us here have had a template biopsy, and it's absolutely nothing to worry about. It's done under general anaesthetic as a day procedure. You'll have a spectacular bruise on your perineum (the skin between your testicles and back passage) and it'll be sore to sit down for a day or two, but that's it. You'll probably pass a bit of blood when you pee for a couple of weeks after. You'll get the results a couple of weeks later.

Don't worry about it.

Chris

User
Posted 21 Aug 2018 at 08:50

Thanks, not sure which route to take. Was given a radical prostatectomy option when first diagnosed in April, but now wondering why I'm having a template biopsy. 

I have been having regular PSA Tests for last 4 years, every 6 mths, lately every 3.

Can't see what active surveillance is going to achieve now when cancer is confirmed ??

Appreciate your response

Alistair

User
Posted 21 Aug 2018 at 08:53

Thanks Chris

Have read a little about template biopsy, just unsure what the necessity for one is if my initial biopsy showed I had a T1c tumour.

Hopefully it'll provide my specialist with a more complete picture of my cancer

Cheers

Alistair

User
Posted 21 Aug 2018 at 09:03
That's exactly it. A TRUS biopsy (which you've presumably already had?) can only take samples from part of the prostate. The template biopsy can get at the whole of the prostate and is just to make sure there's nothing more active lurking in the parts that the TRUS couldn't get at. When I had mine, the TRUS had shown Gleason 3+3, and the template subsequently found a very small amount of 3+4. I've gone down the hormone therapy followed by radiotherapy route - I started my hormone therapy a few days ago.

Best of luck and keep us updated!

Chris

User
Posted 21 Aug 2018 at 09:34
Go for your template biopsy as advised. Then you and your clinicians will have a more complete picture of where you stand. If your score is still 3+3=6, happy days!

Old Barry here read that some doctors are saying another term should now be used for Gleason 6, as the words “The Big C” strike fear and dread into people. Understandable of course, but how dangerous it is depends on what kind of ”C” it is and what stage it’s at.

You may or not be reassured that if you had critical illness insurance with, say, Aviva, they would not pay out on a Gleason 6 as it is not classed as ‘life-threatening’.

Best of luck, anyway.

Cheers, John.

User
Posted 21 Aug 2018 at 09:37

Chris,

That has confirmed what I thought. The template biopsy can show up different cancer results than the TRUS biopsy.

Im 50 and retire from my current role in a couple of years, so would like to get the matter sorted out ASAP. 

Really appreciate your advice,

Cheers 

User
Posted 21 Aug 2018 at 09:38

Cheers John

User
Posted 21 Aug 2018 at 12:30

Originally Posted by: Online Community Member

Thanks, not sure which route to take. Was given a radical prostatectomy option when first diagnosed in April, but now wondering why I'm having a template biopsy. 

I have been having regular PSA Tests for last 4 years, every 6 mths, lately every 3.

Can't see what active surveillance is going to achieve now when cancer is confirmed ??

Appreciate your response

Alistair

Active surveillance is a perfectly proper option, it might be that no intervention is required during your lifetime. Many of us have had, or still have, cancer cells, but they grow so slowly that old age finishes us off before it gets to be a problem.

Why go through a nasty surgery and potential incontinence just in case.? PC is different from most other cancers which can spread rapidly and before you know it, it's too late. It's so slow that many GPs won't investigate "just in case"

User
Posted 21 Aug 2018 at 21:41
Hi Alistair,

I did reply to your situation to which you referred on another thread. Have you found the time to listen to the talk I linked to and recommended?

The thought raised by Tykey is worthy of consideration. Also, John noted that I had said that there was a move ahead to stop Gleason 6 as being considered as cancer. The proposal is to term it as IDLE, which stands for Indolent Lesion of Epithelial origin.

This is an abstract from a well referenced paper on the subject of treatment and overdiagnosis :- Abstract

A vast range of disorders—from indolent to fast-growing lesions—are labelled as cancer. Therefore, we believe that several changes should be made to the approach to cancer screening and care, such as use of new terminology for indolent and precancerous disorders. We propose the term indolent lesion of epithelial origin, or IDLE, for those lesions (currently labelled as cancers) and their precursors that are unlikely to cause harm if they are left untreated. Furthermore, precursors of cancer or high-risk disorders should not have the term cancer in them. The rationale for this change in approach is that indolent lesions with low malignant potential are common, and screening brings indolent lesions and their precursors to clinical attention, which leads to overdiagnosis and, if unrecognised, possible overtreatment. To minimise that potential, new strategies should be adopted to better define and manage IDLEs. Screening guidelines should be revised to lower the chance of detection of minimal-risk IDLEs and inconsequential cancers with the same energy traditionally used to increase the sensitivity of screening tests. Changing the terminology for some of the lesions currently referred to as cancer will allow physicians to shift medicolegal notions and perceived risk to reflect the evolving understanding of biology, be more judicious about when a biopsy should be done, and organise studies and registries that offer observation or less invasive approaches for indolent disease. Emphasis on avoidance of harm while assuring benefit will improve screening and treatment of patients and will be equally effective in the prevention of death from cancer.

Taken from this paper which includes also includes a specific heading for Prostate :- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4322920/

Barry
User
Posted 21 Aug 2018 at 21:59

Thanks Barry

It would seem to make sense really, as that C word is a real game changer.

I'm sure my situation would be classed as IDLE but I'm a little sensitive considering my father's diagnosis in the past.

I will have my template biopsy and address these points with my specialist.

I don't want surgery if I genuinely don't need it, but like so many others, the presence of any cancer cells is enough to have a serious impact on the ability to relax and move forward.

I'll have a listen properly and digest the related literature, been in work all day. Still here now !!!

 

Thanks again

Alistair

User
Posted 21 Aug 2018 at 22:13

Hold on a minute Alistair

How were you diagnosed with G3+3 and a clinical staging of T1c without a biopsy? Have you had an earlier biopsy. If so they might want to do an MRI to see if the Cancer is detectable and the leasion confined or has capsular contact to help assist in a watchful waiting approach. There are plenty of alternate options for a T1c to consider

Fresh

Edited by member 21 Aug 2018 at 22:15  | Reason: Not specified

Base jumping without a parachute should be frowned at, never criticised. Fresh

User
Posted 21 Aug 2018 at 22:17

Yeah

Have had an MRI and TRUS biopsy.

Flagged up a T1c tumour,midline. 8 out of the12 core samples 3+3

Now a template biopsy is scheduled at specialists request.

User
Posted 21 Aug 2018 at 22:28

Why do they need the second biopsy. You have everything you need to define a treatment path. They must have explained that to you.

Fresh

 

Base jumping without a parachute should be frowned at, never criticised. Fresh

User
Posted 21 Aug 2018 at 22:33

Fresh

That's the dilemma I'm facing.

I can only think that my particular specialist prefers this course of action.

It's something I will discuss with him, but I do understand from previous responses to me that they can find different grades of cancer cell deeper inside the prostate. That may alter my treatment plan. 

I'll keep the thread updated in due course

Thanks for your message,appreciated

 

User
Posted 21 Aug 2018 at 23:49

Originally Posted by: Online Community Member

Fresh

That's the dilemma I'm facing.

I can only think that my particular specialist prefers this course of action.

It's something I will discuss with him, but I do understand from previous responses to me that they can find different grades of cancer cell deeper inside the prostate. That may alter my treatment plan. 

I'll keep the thread updated in due course

Thanks for your message,appreciated

 

 

Three likely possibilities come to mind:-

a) consultant wants to be sure it is a G6 before recommending AS to you 

b) your PSA is higher than s/he would have expected for a low level cancer diagnosis

c) one or more of the cores showed a high % cancer OR in one or more cores, the cancerous cells were close to the edge

"Life can only be understood backwards; but it must be lived forwards." Soren Kierkegaard

User
Posted 22 Aug 2018 at 08:00

Originally Posted by: Online Community Member

Why do they need the second biopsy?

Fresh

Because in a TRUS biopsy they take between 6 and 12 core samples, and in my template biopsy they took 42. I had a perineum like a pin-cushion! But no pain apart from the first two post-op wees where the urethral catheter had been fitted and removed.

Thus it’s much more accurate and if he’s lucky enough to go on Active Surveillance, i.e. do nothing, carry on living as normal and just have quarterly blood tests, a template biopsy will enlighten him and his clinicians as to whether anything more sinister is lurking outside of those 6 to 12 samples, and whether AS is appropriate. Fingers crossed 🤞 

Cheers, John

Edited by member 22 Aug 2018 at 10:03  | Reason: Not specified

User
Posted 23 Aug 2018 at 00:17

When my husband was diagnosed with a G6 (3+3) and recommended a. radical prostatectomy we found this an interesting read:

Invasion of the Prostate Snatchers: An Essential Guide to Managing Prostate Cancer for Patients and Their Families

https://www.amazon.co.uk/dp/1590515153/ref=cm_sw_r_cp_api_wSEFBb6ZJ5XXK

 

Also the results of the ProtecT trial from this site are interesting for a low risk diagnosis.

My husbands diagnostic route did involve a MPmri scan and a template biopsy and with his dad dying from prostate cancer a few months before diagnosis I would not have been happy to pick a treatment route wthout these so it sounds sensible to have the offered second biopsy to confirm the diagnosis.

Good luck

Clare

Edited by member 23 Aug 2018 at 00:21  | Reason: Not specified

User
Posted 23 Aug 2018 at 09:08

Clare,

I will check the book out and thanks for your comments

Hope OH is progressing well

Alistair

 
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