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Cialis'Tadalafil and Grapefruit

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User
Posted 31 Aug 2018 at 09:32

Hi All

I am now 19 months post RARP and have been taking 100mg Viagra approx every other day. There is some ED improvement but not satisfactory yet. Also using a pump mostly 3 times a day to avoid atrophy and produce a more substantial erection.

I had right side nerve sparing only and I'm aware that the end of the window for nerve healing is approaching. Some say 2 years some say 3.

Having read and posted in several threads on this I have taken on board the advice and got a prescription for Tadalafil 5mg\day, although I have to pay for it ( I am outside of the UK and the local health service will only pay for Viagra) on the basis that it will provide permanent improved blood flow to the healing area rather than just the few hours with Viagra.

I have read that consuming grapefruit while taking Tadalafil can increase its affect bacause Tadalafil is poorly absorbed and absorbtion is improved by grapefruit juice. It is actually a warning on the medication advice. I was thinking then, that one could effectively increase the effectiveness of the 5mg dose quite safely just by consuming the grapefruit.

Anyone tried this, either on purpose or otherwise? Any thoughts?

Cheers

Bill

User
Posted 31 Aug 2018 at 11:30
Bill, I really wouldn't advise this. The reason that you're recommended not to drink grapefruit juice with a lot of medicines is that (as you say) it blocks the action of a specific enzyme in the wall of the small intestine that destroys many drug molecules, thus increasing the amount that gets into your bloodstream. However, getting more into your blood also increases the likelihood of toxic side-effects. It's worth adding that you need to drink a LOT of grapefruit juice (a litre a day or more) for this effect to become noticeable. The occasional glass won't do anything.

Cheers,

Chris

User
Posted 31 Aug 2018 at 16:50
Thanks Chris

Cheers Bill

User
Posted 28 Dec 2022 at 10:21

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Edited by member 30 Jul 2023 at 05:22  | Reason: Not specified

 
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