Time for my own thread I think...
There's a timeline in my bio, but here's a quick precis: Initial GP visit 30 Dec 2014 aged 56 with sudden severe pain in groin and lower back, PSA was 41.8. Diagnosed Feb 2015 with Advanced PCa Gleason 4+3, T4 N0 M1, mets in lower lumbar L2. Started Triptorelin/Decapeptyl HT followed by Docetaxel 'early' chemo. PSA dropped and remained stable <1 through to end of 2016 then rose steadily in 2017. Had RT to L2 to reduce spine met Feb 2018. Started on Abiraterone with the IPATential150 trial in April 2018, and PSA dropped to 0.44. Sadly it started rising again in September reaching 2.6 beginning of January this year and was signed off the trial due to disease progression and swelling at L2. Good news is that organs and lymph are all clear.
So where now?
Currently I'm waiting for the referral back to my local hospital for more RT to L2 to knock that back again. I'm also going to get more chemo, Cabazitaxel/Jevtana there at some point. Anyone had that? How does it compare to Docetaxel?
Another possibility is continuation of Abiraterone or maybe try Enzalutamide. I can have either as my previous Abiraterone was funded by the trial, not the NHS. Thing is, what to choose? - Is the PSA rise due to the Abi failing or just general progression - Would Enzo work if Abi is failing?