Hi Steve
my hubby is five years and going strong too!
he tried enzalutamude last year and it didnt reduce his psa atall. it is currently 4800.
after enzo he went on to radium 223 as his bone mets were getting worse, he has them in spine, pelvis, thigh, ribs, skull, well oretty much all over and lymph spread too.
anyway in the summer he started 10 cycles of docetaxel as radium 223 sent his psa from about 90 to 6000.
so he managed 8 cycles but tven ge develiped neuropathy which is tingling in hands and feet.
anyway he found the chemo no where near as bad as he thought, the very word fills you with horror doesnt it?
our daughter gave him a very short hair cut when his quite long hair began to fall out, i beleive this helped because he didnt lose any more. He had some nausia but this was controlled with metoclopramide tablets. the procedure itself was very civilised, our local hospital has a very pleasent chemo unit with lovely staff.
he says the worst part is the total exhaustion, he described it as walking through treacle.
he feels much better for having it, his pain has eased and hes not sick like he was on radium but 1 month post chemo his psa is rising out of control again.
we have been given permission to go away on holiday in the sun fir two weeks then when we get back it looks line the final tool in the armour of cebazetaxel.
we have decided to not fet too obsessed with osa figures, after five years on this journey its about how you feel from d ay to day.
i will add though that our onco only ever gave hubby 80% doseage on the chemo and i think that help ed him cope so well.
best wishes and good luck
linda g