Originally Posted by: Online Community Member
I have just started on Prostap injections I started in December, January and February. My March injection will be for 3 months.
I also have type 2 diabetes, since starting with the injections my blood sugars have doubled. Has anyone had a similar problem?
I'm on Zoladex, but it's probably a side effect of all the LHRH drugs.
I'm not diabetic, but my fasting glucose level went from typically 4.1-4.6 to 5.6 in the first 12 weeks on Zoladex. If I had started out at the upper end of normal, it would have pushed me into pre-diabetes.
Metformin, an anti-diabetic drug, has been shown to be beneficial at delaying or stopping PCa recurrence, and there's currently a STAMPEDE trail arm trying to work out the optimum dose for this case. None of the other anti-diabetic drugs have any beneficial impact on PCa treatments. Although it wouldn't normally be prescribed for diabetes until you are over 6 (I'm not sure how far over 6), I asked my GP and he was happy to put me on it on the basis of the improved cancer outcomes. It might stop me going into pre-diabetes too. Also, it won't give you a hypo if you aren't diabetic (according to my GP).
Swagman, since you know you are diabetic, you are presumably already on treatments, so I don't know how relevant Metformin is for you. If your treatment includes anti-diabetic drugs other than Metformin, you might consider asking about switching to Metformin to get the PCa treatment benefits from it too, but that won't fix your blood glucose levels. You need to go back to your diabetic nurse (or whoever), and explain the HT is changing your blood glucose levels (which is expected at least for Zoladex).