I'm interested in conversations about and I want to talk about
Know exactly what you want?
Show search



Blood in urine post biopsy

Posted 22 Jul 2019 at 20:29

Apologies if this is posted in wrong forum/topic

Would welcome thoughts/guidance re blood in urine, post biopsy

I have previously undergone 2 "standard" TRUS biopsies and suffered no ill-effects/problems (small "bloody" discolouration of urine for 2-3 days as well as blood in ejaculate for 2-3 times).

However have recently had a fusion biopsy and with "training" registrar looking on - this naturally; with the training aspect took quite a bit longer and more samples taken - some needed another attempt ie not enough tissue in sample hence re-try 

So now 5 days later urine is still a bit discoloured - more the colour of a light rose wine!!! 

How long is it in peoples experience that the urine takes to return to "normal"

Not feeling un-well or in any pain, plus no sign of blood in faeces

Thanks - grateful for your thoughts


Posted 22 Jul 2019 at 23:36

I didn't have much in my urine. It only ever showed in the first few cc's when starting to pee, presumably as the first bit of urine washes it out of the urethra through the prostate. If all your urine stream is coloured, that might suggest blood is going into the bladder and mixing with the urine, which I think is not unexpected. If you are on tamsulosin and you are ejaculating, you will likely have some retrograde ejaculation into the bladder (a side effect of tamsulosin), and that could carry blood into the bladder.

I had blood in my semen for 3 weeks, with daily ejaculating. I recall the leaflet for the procedure said that could happen for up to 6 weeks (maybe if you don't flush it out so often - my urologist said don't hold back ejaculating). I can't remember how long it suggested for blood in urine, but it was less - maybe 3 weeks.

Posted 23 Jul 2019 at 07:08
It can take a couple of weeks for all traces of blood to disappear from urine. Nothing to be concerned about.

Best wishes,


Posted 27 Jul 2019 at 22:35

Andy, Chris

Thanks for your comments, I am a little more relaxed after reading your replies.





Posted 09 Oct 2019 at 02:55


Beware of the biopsy. I had a TRUS biopsy with 12 cores taken here in the US. The procedure was not great but not as bad as one might think. About 4 samples from the Apex hurt during the procedure. That night just sore. Yes blood in my urine, stool and ejaculate. That is where routine stopped.


The day after biopsy I had burning urination, pain at the base of my penis and an impossible time trying to pee. Doc thought I may have an infection and gave a week of Sulfa antibiotic. It cleared most of this up but still had some blood in my urine and soreness in my pelvis. It hurt to ejaculate like squeezing a thorn down there and the ejaculate was all just red blood.


I am 14 days after biopsy now. I have pain in my pelvis, and some blood in my urine. It still hurts to ejaculate and the ejaculate is all still fresh red blood. I am on a new antibiotic for 21 days Doxycycline. No relief in sight. Doc says it's not uncommon to have these side effects for a month.


I know your thinking I'm old or sick and have these problems. I am 45, in great health and don't take any medications regularly. I'm in great shape except for this. The day before biopsy I had no pain, no urinary problems and completed my Crossfit work out. As of now I can't exercise without pain.


My biopsy was for a PSA of 5.1 with free PSA of 25%. My results were all benign. I regret ever having the biopsy.


Posted 09 Oct 2019 at 08:02
Unfortunately a biopsy is the only way to know for certain whether or not you have cancer, Toby. In a small percentage of cases there can be complications, but this is not normal. Generally, a couple of day of soreness and blood in the urine and semen is as far as it goes.

Happy to hear that your biopsy came back "all clear", but with a PSA of 5 at your young age it's completely understandable that you had the procedure.

Best wishes,


Posted 09 Oct 2019 at 11:17

TRUS is being phased out in the UK, and a transperineal version of it is replacing it (not the template biopsy).

This is because of the infection risk of piercing the rectum - around 3% of TRUS procedures result in infections, and this figure has been rising due to increasing antibiotic resistance, and some of these require hospital admission and can become full sepsis.

PCUK were quite key in jointly developing the new procedure with one of the hospitals (I forget which one), the key aspect of which was developing a local anesthetic procedure for the perineum so that the procedure can be performed in an outpatient setting (versus the transperineal template biopsy which was traditionally a theatre procedure under GA, but is also being tried as an outpatient procedure in some places now).

Forum Jump  
©2021 Prostate Cancer UK