I'm interested in conversations about and I want to talk about
Know exactly what you want?
Show search

Notification

Error

VIagra query

User
Posted 27 Feb 2020 at 07:15

Hi all. Quick background first – I was Gleason 9, PSA 22 and had RARP in Jan 17, immediately followed by RT and HT due to positive margins and cancer found in lymph nodes. Fast forward to now, and my PSA is holding at <0.003, lymphedema, adhesions mostly cleared up, regained erections (with help!) and libido appears to be back, unlike my wife who left.

Incontinence is mostly under control except when even slightly aroused, in which case my urethra thinks it’s OK to empty. Not comfortable, and certainly not conducive to meeting a new partner. Anyway, miracles happened and I’ve met an amazing woman who is fine with me as I am, leaks and all. Never thought that would happen!

So libido is back with a vengeance, and I finally get a chance to experiment with chemical assistance. And this is where we finally get to my question. I have always been on Cialis (Tadalafil) 5mg daily (thanks GP) , and although that seems to have worked in maintaining blood flow and partial function over the last three years, come the event it didn't perform. So I tried not using Tadalafil and tried 100mg Viagra (Sildenafil). Kerching! Even carried on working in the morning?! I know that shouldn’t be the case with Sildenafil, so maybe a combination of that and a bit of residual Tadalafil?

Two days ago I went to my GP to ask for a meds swap – could I have Sildenafil instead of Tadalafil please. I told her I’m aware that there will be restrictions on how much she can prescribe, so she looked it up and said no, it can be daily. So now I’m prescribed 100mg Sildenafil daily. Having a sex life that requires that amount will almost certainly have fatal consequences!

The question is essentially views on Tadalfil vs. Viagra, or combinations of them. I know we are all individual and respond differently, but is there a combination that any of you have found works best? Either way, I’m going to enjoy experimenting! Also, I’m guessing 100mg a day is not to be recommended?  A great bit of info from this is it seems GPs can prescribe, so please guys, chase your CCGs on this. And for those who still can’t convince their GPs to prescribe what is due, it seems I may have some spare!

User
Posted 27 Feb 2020 at 07:15

Hi all. Quick background first – I was Gleason 9, PSA 22 and had RARP in Jan 17, immediately followed by RT and HT due to positive margins and cancer found in lymph nodes. Fast forward to now, and my PSA is holding at <0.003, lymphedema, adhesions mostly cleared up, regained erections (with help!) and libido appears to be back, unlike my wife who left.

Incontinence is mostly under control except when even slightly aroused, in which case my urethra thinks it’s OK to empty. Not comfortable, and certainly not conducive to meeting a new partner. Anyway, miracles happened and I’ve met an amazing woman who is fine with me as I am, leaks and all. Never thought that would happen!

So libido is back with a vengeance, and I finally get a chance to experiment with chemical assistance. And this is where we finally get to my question. I have always been on Cialis (Tadalafil) 5mg daily (thanks GP) , and although that seems to have worked in maintaining blood flow and partial function over the last three years, come the event it didn't perform. So I tried not using Tadalafil and tried 100mg Viagra (Sildenafil). Kerching! Even carried on working in the morning?! I know that shouldn’t be the case with Sildenafil, so maybe a combination of that and a bit of residual Tadalafil?

Two days ago I went to my GP to ask for a meds swap – could I have Sildenafil instead of Tadalafil please. I told her I’m aware that there will be restrictions on how much she can prescribe, so she looked it up and said no, it can be daily. So now I’m prescribed 100mg Sildenafil daily. Having a sex life that requires that amount will almost certainly have fatal consequences!

The question is essentially views on Tadalfil vs. Viagra, or combinations of them. I know we are all individual and respond differently, but is there a combination that any of you have found works best? Either way, I’m going to enjoy experimenting! Also, I’m guessing 100mg a day is not to be recommended?  A great bit of info from this is it seems GPs can prescribe, so please guys, chase your CCGs on this. And for those who still can’t convince their GPs to prescribe what is due, it seems I may have some spare!

User
Posted 17 Jun 2021 at 22:04

Don't know what does this has to do with viagra and other stuff like that but let me explain one thing. Don't ever buy such medicines if you haven't first talked to your doctor. Just don't! Cause I remember doing this s*** and lying after that in bed with a great allergy instead of great sex. Thank god my doctor helped me and prescribed the medication I really needed:)

Edited by member 17 Jun 2021 at 22:05  | Reason: Not specified

Show Most Thanked Posts
User
Posted 27 Feb 2020 at 21:30
What a fantastic update - I am so happy for you.

Is the GP still willing to prescribe the Cialis as well as the large amount of Viagra? If so, John's ED nurse allowed him both for a few years on the understanding that if he was planning on using the Viagra later, he shouldn’t have the Cialis that morning.

If not, it might be that the Cialis has done its job in keeping your penis healthy and you will be fine now just with Viagra for events.

"Life can only be understood backwards; but it must be lived forwards." Soren Kierkegaard

User
Posted 28 Feb 2020 at 09:07
Good news on the romance front Graham.

I am also prescribed both. I get daily 5mg Tadelafil and 16 sildenafil per. Month, so 100mg every other day. I take the Tadelafil every evening and if I'm also taking sildenafil that evening I bite off 3 three quarters and save the rest. Max dose for Tadelafil is 20mg every 24 hours and sildenafil is 100mg every 24 hours. So that's a quarter of one and three quarter of the other max dose wise. Many times I have taken the full 100mm several days in a row with no ill effects.

Good luck

Cheers

Bill

User
Posted 28 Feb 2020 at 09:46
Thanks both for the replies. This is all very new territory! I still have 4+ months of Tadalafil in reserve, so that gives me scope to experiment and if required, back to GP to tailor requirements again. I don't intend on having Tadalafil and Sildenafil both on the same day, but the Tadalafil does has residual effect. I do feel very grateful for having a engaging GP, I know that unfortunately doesn't apply to all the men here.

cheers

Graham

User
Posted 28 Feb 2020 at 13:37
Good news that you’re able to take both drugs, Graham. I tried Viagra as an experiment a couple of times some years ago and it gave me a splitting headache on both occasions!

Best wishes,

Chris

User
Posted 28 Feb 2020 at 16:21
My friend in America, then aged about seventy, went to his doctor for Viagra (Sildenafil).

Doctor: ‘How many do you need, I can prescribe you six month’s worth?’

‘Oh, give me a hundred’. After the Doc had got over the shock, the script was issued.

My mate tried one and having got over the fainting fit, never took any of the other 99!

He’s been quite happy with Cialis (Tadalafil 5mg daily), despite being in his eighties now!

Cheers, John.

User
Posted 28 Feb 2020 at 17:32
Am I in the wrong here ??? As far as I’m aware the full dose of any PDE5 tablet should only be taken 3 times per week and with a 24 hr gap between doses. This advice seems incorrect to me !! Lyn??

If life gives you lemons , then make lemonade

User
Posted 28 Feb 2020 at 21:47

NICE updated their guidelines in August 2019. Quite interesting that so many CCGs are ignoring it.

- normal dosing would be 4 tablets or injections per month on the basis that the average 40 - 60 year old has sex once per week
- however, the prescribing doctor should take into account what the patient says about the frequency of their sex life and can prescribe more than 4 per month
- daily Cialis should be prescribed instead for men who are likely to want to have sex twice a week or who value spontaneity
- maximum dose of viagra is 100mg, and the maximum frequency is once per day
- mixing them is not approved by NICE

https://cks.nice.org.uk/erectile-dysfunction#!scenario 

"Life can only be understood backwards; but it must be lived forwards." Soren Kierkegaard

User
Posted 28 Feb 2020 at 21:54

Two people I've counseled and told to go to their GP's and ask for 5mg daily Tadalafil plus a small allowance of 20mg event doses have come back with daily dose prescriptions for both 5mg and 20mg. (Different GPs.) I think this whole area is not well understood by many GPs.

Since I don't necessarily see people again (particularly if the drugs work), and therefore wouldn't always know they'd been given the wrong prescriptions, what I tend to suggest now is ask for 5mg daily, and when you want an event dose, take the next one or two day's 5mg doses today too, and then skip those days to get back in sync. You'll still maintain your continuous low level dosing because of the long half life, but you're not at any risk of excess dosing.

User
Posted 01 Mar 2020 at 09:55

Originally Posted by: Online Community Member
Am I in the wrong here ??? As far as I’m aware the full dose of any PDE5 tablet should only be taken 3 times per week and with a 24 hr gap between doses. This advice seems incorrect to me !! Lyn??

The side effects of PDE5 inhibitors are well known, but does anyone know the possible consequences of long term slight overuse?

Cheers

Bill

User
Posted 01 Mar 2020 at 14:21

Bill

I was prescribed a daily 100 mg dose of sildenafil. Took it for a good few months then dropped it to 50mg. I took mine at night and did not notice any side effects, apart from the blue tinge and the snuffles.

Thanks Chris

User
Posted 01 Mar 2020 at 14:39
The blood vessels in the corpora cavernosa in the penis which control erections are similar to the blood vessels in the nasal passage, so any drug which increases blood flow (vasodilators) down below can cause your nose to become blocked and sniffly.

When I did have sex, pre-op, if I had a very sexy thought I would often sneeze!

Cheers, John.

User
Posted 01 Mar 2020 at 23:27

As I snuffled a little, I was thinking to myself, is this Tadalafil, or coronavirus? ;-)

PDE5 inhibitors are not directly vasodilators. The vasodilator in this case is the nitric oxide, which your penis has produced in response to the arousal and signalling from the brain. PDE5 destroys nitric oxide, so that your erection goes down again when the arousal and nitric oxide generation stop. The PDE5 inhibitor prevents the PDE5 destroying the nitric oxide, so that if you aren't producing much nitric oxide (fewer nerves or low libido), it gets a chance to build up to a working level.

None of the PDE5 inhibitors are only PDE5 inhibitors. They are all, to differing degrees PDE1, PDE6, and PDE11 inhibitors too, and these lead to the side effects. PDE6 is found in the photoreceptor cells in the retina, and inhibiting that is what causes the blue tinge some people see with Viagra/Sildenafil. The others change blood flow in the brain and nasal cavities, causing headaches and blocked noses in some people.

If the side effects are an issue for you, try a different PDE5 inhibitor.

Edited by member 02 Mar 2020 at 07:07  | Reason: Not specified

User
Posted 02 Mar 2020 at 06:12
All good info above, but does anyone know what the long term effects of prolonged slight overdosing would be?

Quite sometime back I remember reading about a trial where men were given high doses of Viagra, 200mg/day I think and the conclusion was that it was safe at that dose.

Cheers

Bill

User
Posted 24 Mar 2020 at 06:49

I am just about to run out of the Tadalafil (5mg daily) that I left hospital with post RP and set up repeat prescriptions with my GP. 

The Clinical Nurse Specialist told me the recommended 4 a month was originally simply a guideline to GPs from when Viagra was under patent and expensive.  They were worried it’s widely reported successes would bankrupt the NHS!

User
Posted 22 May 2020 at 13:37

Just read your post. I am thinking of combining the 2 tablets as well. I started taking 5mg dailies before my op and wow. It has now been 12 months since my op with both sets of nerves saved. Still taking the 5mg dailies with a semi deflated football results. So I intend still to carry on with the daily 5mg tadalafil in the morning and also taking sildenafil 50mg at first on demand to see if there is any improvement. I have added my own post ( alternative to tadalafil ), so just trying to get as much advice and information as possible.

User
Posted 22 May 2020 at 15:21

Originally Posted by: Online Community Member
All good info above, but does anyone know what the long term effects of prolonged slight overdosing would be?

Quite sometime back I remember reading about a trial where men were given high doses of Viagra, 200mg/day I think and the conclusion was that it was safe at that dose.

Cheers
Bill

 

NICE has approved sildenafil at a maximum of 100mg per day where the doctor has information to suggest that the patient would benefit - in essence, if a man says that he wants daily sex. However,

a) local CCGs do not have to agree and can decide that in their area a different maximium will be applied - many CCGs are still rationing men to 4 erections per month whether that is by tablet, pellet or injection, and

b) there is no evidence that sildenafil promotes nerve repair and ED recovery in the same was as Cialis / tadalafil so a daily dose of 100mg sildenafil might not do any harm but isn't necessarily going to do any good, either. 

"Life can only be understood backwards; but it must be lived forwards." Soren Kierkegaard

User
Posted 17 Jun 2021 at 22:04

Don't know what does this has to do with viagra and other stuff like that but let me explain one thing. Don't ever buy such medicines if you haven't first talked to your doctor. Just don't! Cause I remember doing this s*** and lying after that in bed with a great allergy instead of great sex. Thank god my doctor helped me and prescribed the medication I really needed:)

Edited by member 17 Jun 2021 at 22:05  | Reason: Not specified

 
Forum Jump  
©2021 Prostate Cancer UK