VIagra query

I am also prescribed both. I get daily 5mg Tadelafil and 16 sildenafil per. Month, so 100mg every other day. I take the Tadelafil every evening and if I'm also taking sildenafil that evening I bite off 3 three quarters and save the rest. Max dose for Tadelafil is 20mg every 24 hours and sildenafil is 100mg every 24 hours. So that's a quarter of one and three quarter of the other max dose wise. Many times I have taken the full 100mm several days in a row with no ill effects.

Good luck

Cheers

Bill

Best wishes,

Chris

Two people I've counseled and told to go to their GP's and ask for 5mg daily Tadalafil plus a small allowance of 20mg event doses have come back with daily dose prescriptions for both 5mg and 20mg. (Different GPs.) I think this whole area is not well understood by many GPs.

Since I don't necessarily see people again (particularly if the drugs work), and therefore wouldn't always know they'd been given the wrong prescriptions, what I tend to suggest now is ask for 5mg daily, and when you want an event dose, take the next one or two day's 5mg doses today too, and then skip those days to get back in sync. You'll still maintain your continuous low level dosing because of the long half life, but you're not at any risk of excess dosing.

Bill

I was prescribed a daily 100 mg dose of sildenafil. Took it for a good few months then dropped it to 50mg. I took mine at night and did not notice any side effects, apart from the blue tinge and the snuffles.

Thanks Chris

As I snuffled a little, I was thinking to myself, is this Tadalafil, or coronavirus? ;-)

PDE5 inhibitors are not directly vasodilators. The vasodilator in this case is the nitric oxide, which your penis has produced in response to the arousal and signalling from the brain. PDE5 destroys nitric oxide, so that your erection goes down again when the arousal and nitric oxide generation stop. The PDE5 inhibitor prevents the PDE5 destroying the nitric oxide, so that if you aren't producing much nitric oxide (fewer nerves or low libido), it gets a chance to build up to a working level.

None of the PDE5 inhibitors are only PDE5 inhibitors. They are all, to differing degrees PDE1, PDE6, and PDE11 inhibitors too, and these lead to the side effects. PDE6 is found in the photoreceptor cells in the retina, and inhibiting that is what causes the blue tinge some people see with Viagra/Sildenafil. The others change blood flow in the brain and nasal cavities, causing headaches and blocked noses in some people.

If the side effects are an issue for you, try a different PDE5 inhibitor.

Edited by member 02 Mar 2020 at 07:07  | Reason: Not specified

I am just about to run out of the Tadalafil (5mg daily) that I left hospital with post RP and set up repeat prescriptions with my GP. 

The Clinical Nurse Specialist told me the recommended 4 a month was originally simply a guideline to GPs from when Viagra was under patent and expensive.  They were worried it’s widely reported successes would bankrupt the NHS!

NICE has approved sildenafil at a maximum of 100mg per day where the doctor has information to suggest that the patient would benefit - in essence, if a man says that he wants daily sex. However,

a) local CCGs do not have to agree and can decide that in their area a different maximium will be applied - many CCGs are still rationing men to 4 erections per month whether that is by tablet, pellet or injection, and

b) there is no evidence that sildenafil promotes nerve repair and ED recovery in the same was as Cialis / tadalafil so a daily dose of 100mg sildenafil might not do any harm but isn't necessarily going to do any good, either.