The Colchicine works as a quick action relief medication, made from crocus or something it is a poison but stops the gout pain pretty quickly, it is only taken for a short period of maybe a day or so. The corticosteroid ( Prednisolone) is taken as a course of however many, I try to take as few as possible, one or two a day for a couple of days but your GP will advise. They somehow suppress the gout and give longer term relief.
OK on your big toe, I get it mostly in my foot bones but sometimes in my big toe.
John