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Serum sex hormone binding globulin level (SHBG)

Posted 18 Dec 2020 at 00:22

I had a set of blood tests last week which included Testosterone (0.4 nmol/L - on hormone therapy). The lab has added a new test result with a testosterone test since I last had it - Serum sex hormone binding globulin level (SHBG). This is the protein that most of the bound (non-free) testosterone binds to, so I think it's an alternate way to report free Testosterone.

The normal range is 21-77nmol/L. Mine was 90, so it was flagged up on the computer.

Checking research papers, it seems that high levels of SHBG is a marker for low bone density and osteoporosis. So I'm thinking, is this just indicating what I already know, that hormone therapy will have reduced my bone density, or is it another factor on top of that? The reason for this relationship is probably that high levels bind lots of your testosterone, making it unavailable for things like good bone health.

So I was just wondering if anyone else knows their SHBG level, and if so, does being high tie-up with being on hormone therapy?

Edited by member 18 Dec 2020 at 12:08  | Reason: Not specified

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