GnRH and LHRH are different names for exactly the same hormone.
GnRH = Gonadotripin Releasing Hormone (i.e. the hormone that releases Gonadotropins).
LHRH = Lutenising Hormone Releasing Hormone (i.e. the hormone that releases Lutenising Hormone).
Gonadotropin is the collective name for Lutenising Hormone and Follicle Stimulating Hormone (FSH). Since there is no hormone which releases just Lutenising Hormone, and the hormone in question releases both Lutenising Hormone and Follicle Stimulating Hormone, GnRH is arguably the more correct term.
If you want to know how these work, watch my lecture How Hormone Therapy Drugs Work. I explain the difference between agonists and antagonists, and why the agonists generate a testosterone flare and the antagonists don't.
Zoladex/Goserelin, Prostap/Luprorein, and Decapeptyl/Triptorelin are all GnRH Agonists.
Firmagon/Degarelix (and soon to appear, Orgovyx/Relugolix tablets) are GnRH Antagonists.
(A minor nit - we should really say they're GnRH-Receptor Agonists or Antagonists, but the -Receptor bit always gets abbreviated out unless you are reading a research paper.)
Edited by member 21 Dec 2020 at 01:21
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