I have had this problem for years - long before I was diagnosed with PCa - more fool me for not going to my GP. The solution I found then still works for me now, with triptoreline and Enzalutimide surging through my system.
It seems in my case to be connected with carbohydrate. Eating a bread roll late in the evening or a heavy carbohydrate meal earlier on reduces nocturnal trips to the toilet from four or more down to one. Last night I had Ryvita with peanut butter (which I see contains sugar) and had none at all. This works for successive nights with declining effect until I have to reset the clock with no carbs at all. Then it can start again.
Clearly insulin is involved. I have had my blood tested for diabetes types I and II, but glucose remains normal. My GP was mildly interested but saw no cause for further investigation. I have tried to find an endocrinologist to explain it, without success.
Might be worth a try?
Edited by member 25 May 2021 at 18:22
| Reason: Typo