Levitra (Vardenafil) tends to be the next line for patients who get headaches with Tadalafil (which itself is better in this respect than Sildenafil (Viagra)).
A urologist told me it's also a common choice for ED due to diabetes.
There's a 4th one too, Avanafil (Spedra). It's claim to fame was fast acting (15 mins) as well as the most expensive, but the same urologist also told me it tends to be the least effective. However, I've come across a few men who've found it's the one that works for them.
As far as I know, it's only Tadalafil which generates muscle pain, and that's because it's also a PDE11 inhibitor. PDE11 is used in muscle and lots of other places - it is remarkable that Tadalafil is a usable drug, never mind that it's overall the most effective of the four PDE5 inhibitors. All the PDE5 inhibitors also inhibit other PDE's but it's different for each one, which is why they have different side effects.
Edited by member 14 May 2021 at 09:10
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