Tadalafil aches and pains

Levitra (Vardenafil) tends to be the next line for patients who get headaches with Tadalafil (which itself is better in this respect than Sildenafil (Viagra)).

A urologist told me it's also a common choice for ED due to diabetes.

There's a 4th one too, Avanafil (Spedra). It's claim to fame was fast acting (15 mins) as well as the most expensive, but the same urologist also told me it tends to be the least effective. However, I've come across a few men who've found it's the one that works for them.

As far as I know, it's only Tadalafil which generates muscle pain, and that's because it's also a PDE11 inhibitor. PDE11 is used in muscle and lots of other places - it is remarkable that Tadalafil is a usable drug, never mind that it's overall the most effective of the four PDE5 inhibitors. All the PDE5 inhibitors also inhibit other PDE's but it's different for each one, which is why they have different side effects.

Edited by member 14 May 2021 at 09:10  | Reason: Not specified

Has anyone suffered with bad aches and pains and stopped taking their daily dose because of them ? 
if so how long did it take for you feel ok and ache free again ? 
I’m really struggling at the moment with terrible pains in my legs, I take loads of other fancy medication for leukaemia as well (6 tablets a day) that might be causing the problem but don’t know which one it is. Obviously can’t stop the leukaemia meds but would like to know how long I would need to stop the tadalafil to see if it reduces the pain 

thanks 

These ED drugs cause annoying NOT terrible pains.  If you have terrible leg pains I suggest you call 111, it could be blood clots or something else that needs attention.