I had a TRUS biopsy and it was absolutely horrendous for the reasons that follow. It seems, after being on this site a good few years that most as above report simply uncomfortable.
When my Uro advised I have a biopsy preceded by an MRI scan I explained immediately that I had had piles for many years and more recently anal fissures. I had also had surgery for the piles which had failed but left me tight so to speak. He had just witnessed my reaction to his DRE five minutes earlier. However his response was "well most men tolerate it" I was as green as grass as the saying goes and had no idea that there might be other options. The appointment was made and GP advised see a colorectal consultant about the piles and fissure first. He prescribed some creams and a colonoscopy. Fortunately the creams cleared the fissure up just in time for the TRUS.
My anxiety level in the 6 weeks or so leading up to the event was through the roof. On the day, I took strong tranquillisers from GP which had no effect what so ever.
Well my turn came and getting the probe in took considerable effort and both the radiologist and I nearly gave in. I remember him telling the nurses that he suspected a prolapse of some sort, just before he succeeded. It was nothing short of agony.
Due to the issues mentioned above the probe simply didn't really fit but was eventually forced in. The actual click of each sample was nothing compared to the pain of this foreign object being inserted where it really didn't belong and staying there far longer than I was happy about. After the event I was a quivering mess.
Before I left the nurse told me and my waiting Wife that if I ever i needed another in the future that she promised "it would be done some other way, no one should go through that". To late it turned out to be positive anyway and I had RARP.
I wish I'd knowen then what I know now from this site that there were options.
Sorry if this scares anyone but I'd hate for someone else to choose a TRUS if they have similar problems as I had now that the options are more accessible.
Good luck with both the procedure and the result
Cheers
Bill