Mixed Acinar and Ductal

User

Posted 26 May 2022 at 22:54

Hi,

My Dad was diagnosed with Prostate cancer last year, Gleason 4+3 = 7 (grade group 3) in 6 out of 12 cores, max 90% involvement. PSA at diagnosis was 3.77. T3a, N0, M0. He is on hormone injections and completed 20 sessions of radiotherapy earlier in the month. His follow up appt is in June, he has already been told he has had the maximum amount of radiotherapy he can have. He needs to do a blood test before his review but it is face to face as they want to review the length of adjuvant hormonal therapy due to Acinar and Ductal morphology.

I can find information on Acinar and Ductal :( separately however the mix is something that i'm struggling to find information on. The nurse at his last appointment made a comment about a follow up in person due to a funny mix of cells, so i assuming it is because his cancer isnt straightforward.

I was just wondering if anyone had an insight or experience?

User

Posted 27 May 2022 at 00:30

You won't find anything about the two combined and it only really matters in the sense of what proportion is ductal. Acinar adenocarcinoma is by far the most common type of prostate cancer so those cells will behave more or less as the doctors expect, based on their many years of data & experience. Ductal adenocarcinoma is less common and more aggressive but almost always found in conjunction with acinar - it would be extremely rare for a man to have ductal without acinar as well.

You can read more about ductal adenocarcinoma here - you will need to scroll down a bit https://prostatecanceruk.org/prostate-information/further-help/rare-prostate-cancer

"Life can only be understood backwards; but it must be lived forwards." Soren Kierkegaard

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