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PSA test after prostatectomy

User
Posted 17 Oct 2022 at 13:01

I'm now 5 weeks after nerves sparing radical robotic prostatectomy. I'm nearly back to normal pre op. Just minor leaking in the afternoon if I get too tired. I have daily walks fo 10,000 to 12,000 steps. Before surgery I was doing 15,000 to 18,000.

In 2 weeks i have a blood test appointment, for psa test before the surgery it was important to avoid excess exercise, ejaculation...

Now that the prostate  has been removed are there still any recommendations about what to avoid in the few days before giving a blood sample? I'm on Tadalafil, can this alter the psa levels?

Edited by member 26 Oct 2022 at 13:08  | Reason: Not specified

User
Posted 17 Oct 2022 at 15:54

The hospital is likely to have a Blood Clinic page on its website where it tells you the times of opening and any paperwork needed.   Usually you need a form signed by the doctor or nurse treating you.  If you just turn up without a form you might have to go to the ward to get one or you could ask the clerk at the Blood Clinic to arrange it.  I wouldn't go on spec without a form, I'd ask about it.

It's usual for them to say have the blood test 1 week before the appointment although in reality I've found the nurse has the result in the afternoon, as I usually go around 9.30.

When you have a prostate they say don't agitate it with exercise etc.  But now you haven't got one.  Nevertheless I always take it easy and do nothing much in the days before the test.

I can't answer as to whether you can exercise officially but I always assume it's better not to just in case.

I also don't know for certain if there are diet effects.  You read all sorts of things about what is good and what is bad for prostate cancer.  Now you haven't got it hopefully though.   In general in the days before the blood test I don't drink alcohol or eat anything unusual.   I look forward to the test as after that is probably the best time to let things rip and there is nothing you can do about the result.  It's always a worry when you have the test.

I can't answer your question about Tadalafel. 

Good luck, Peter

Edited by member 17 Oct 2022 at 15:57  | Reason: Not specified

User
Posted 17 Oct 2022 at 21:06
Now you have no prostate exercise etc will make no difference. You want your next PSA to be zero and nothing you can eat, drink or ride will affect to he reading..
User
Posted 17 Oct 2022 at 21:16

I agree with francij. You have no prostate so nothing you do should produce any PSA.

Personally I would do every action possible that may cause a PSA response: cycling, sex, a strong curry and loads of beer (not necessarily in that order). If there are any cells in you body producing PSA you want to discover them as soon as possible.

Hopefully despite doing everything wrong before the test, it will still come back near zero, because you should not have a single prostate cell in your body.

Dave

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User
Posted 17 Oct 2022 at 15:54

The hospital is likely to have a Blood Clinic page on its website where it tells you the times of opening and any paperwork needed.   Usually you need a form signed by the doctor or nurse treating you.  If you just turn up without a form you might have to go to the ward to get one or you could ask the clerk at the Blood Clinic to arrange it.  I wouldn't go on spec without a form, I'd ask about it.

It's usual for them to say have the blood test 1 week before the appointment although in reality I've found the nurse has the result in the afternoon, as I usually go around 9.30.

When you have a prostate they say don't agitate it with exercise etc.  But now you haven't got one.  Nevertheless I always take it easy and do nothing much in the days before the test.

I can't answer as to whether you can exercise officially but I always assume it's better not to just in case.

I also don't know for certain if there are diet effects.  You read all sorts of things about what is good and what is bad for prostate cancer.  Now you haven't got it hopefully though.   In general in the days before the blood test I don't drink alcohol or eat anything unusual.   I look forward to the test as after that is probably the best time to let things rip and there is nothing you can do about the result.  It's always a worry when you have the test.

I can't answer your question about Tadalafel. 

Good luck, Peter

Edited by member 17 Oct 2022 at 15:57  | Reason: Not specified

User
Posted 17 Oct 2022 at 18:15

Thanks Peter, I agree, I ll stay on the safe side and avoid 3 days prior test any strong activity. Though right now there is not much I'm doing apart walking. 

User
Posted 17 Oct 2022 at 21:06
Now you have no prostate exercise etc will make no difference. You want your next PSA to be zero and nothing you can eat, drink or ride will affect to he reading..
User
Posted 17 Oct 2022 at 21:16

I agree with francij. You have no prostate so nothing you do should produce any PSA.

Personally I would do every action possible that may cause a PSA response: cycling, sex, a strong curry and loads of beer (not necessarily in that order). If there are any cells in you body producing PSA you want to discover them as soon as possible.

Hopefully despite doing everything wrong before the test, it will still come back near zero, because you should not have a single prostate cell in your body.

Dave

User
Posted 17 Oct 2022 at 21:20

Originally Posted by: Online Community Member

Thanks Peter, I agree, I ll stay on the safe side and avoid 3 days prior test any strong activity. Though right now there is not much I'm doing apart walking. 

 

That is flawed thinking, I think - for robust monitoring in the future, you want to be behaving in very similar ways before each PSA test and do you really want to spend the rest of your life having to remember not to do anything for 3 days before each test. Much better to just go about your normal business. 

"Life can only be understood backwards; but it must be lived forwards." Soren Kierkegaard

User
Posted 18 Oct 2022 at 12:15

Eric, I have asked medically qualified people about how some actions effect PSA results after surgery and other treatments. There does not seem to be detailed analysis of all situations of what actions effect results. I assume that is because the medics do not feel the need to get the information some of us would like to see.

There have been a few studies on the pre surgery PSA effects caused by cycling, some of which say the PSA was elevated for as little as 48 minutes.

As already said consistency before the test us probably the way to go, but how far do you go. My PSA has often fluctuated, many of my blood tests were taken at the hospital, so the blood was tested with an hour, other tests where done at our regional blood service, did the four hour delay and five mile journey to the lab affect the blood sample.

Not confirmed,did the COVID vaccine have an effect on the PSA results. There are some drugs that affect PSA reading, do we know what other food or drink affect the results.

My oncologist thinks it is our blood samples that are unreliable.I had my blood taken and put in two separate vials and sent to the same lab at the same time they came back with a difference of 0.01.

Thanks Chris

 

 

User
Posted 18 Oct 2022 at 12:53

Thanks Chris, good to know about your experience. Like many results and tests about prostate cancer, there is still more to learn. Well what ultimately matters to me is this 1st post surgery appointment in 2 weeks when I hope, I'll  have the results of the lab analysis of the prostate plus the PSA. 

User
Posted 18 Oct 2022 at 16:34

Some people are more risk tolerant or deny there are risks but we each decide for ourselves.  I'm fortunate in having a lucky pair of underpants that I wear at psa tests, although they let me down last December.

I wish someone could set up a tour of a lab and demonstrate a psa test and the calibration of the instrument.  I'm a bit obsessive about it and worked out trends if my psa had varied by 0.001.  That's the difference between say 0.06 and the next higher or lower result.

I've read that some surgeons leave behind tiny bits of prostate and that very low levels of psa can be generated outside the prostate.  If you have a psa test down to say 0.02 or less it might show up although I've also read that below 0.03 a change of 0.01 could be within bounds of instrument error.  My hospital tests to <0.05, the neighbouring hospital <0.06 and others are <0.1.  As my psa reached 0.09 I felt some relief in knowing some people wouldn't even know that, so it should be OK.   I'm pleased I'm aware as I'd have been discharged last December and then tested only annually, i.e. next December.

There are people with a stable psa at higher levels such as 0.09.   If that was mine I'd be trying for consistent conditions.  Not going to the gym or having a few drinks for the previous few days isn't much, I'd do more if I knew what was worth it.  I try to go at 9.30am and have the same breakfast along with a cup of water to help the blood come out and perhaps dilute it.  The phlebotomist told me to have the drink as the blood didn't come out.

One of the great things of this forum is the different attitudes people have towards their treatment choices.  I'm aware of 2 people who've gone a lot further than I'd tolerate and they marched on defiant as examples, one has dropped out, perhaps as an example of composure or sang froid as they say, or perhaps other.

User
Posted 18 Oct 2022 at 17:27
Thank for your answer Peter. I asked the Urology at my hospital to confirm the booking procedure for a post op PSA test and if there are any requirements before the test. They refer me to Prostate Cancer UK.... with a link to PSA blood test. So no information available when the PSA producing plant (prostate) has gone.

Anyway, I was on active surveillance for 4 years with psa every 3 months and always made sure to follow the same routine before the tests. It never bothered me.

 
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