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Posted 02 Mar 2024 at 15:59

Why is it that some men with a PSA in the hundreds have a clear whole body and bone scan,when men with a PSA of 30 can have extensive metastatic disease?

 

Edited by member 03 Mar 2024 at 13:33  | Reason: Not specified

User
Posted 02 Mar 2024 at 19:48

PSA isn't an indication of how aggressive or how extensive the cancer is.

Some prostate cancers produce lots of PSA into the blood stream, and some others (in particular some aggressive ones) lost the ability to produce PSA at all.

At the extremes, I've come across a couple of cases of PSA in the 600's which wasn't metastatic although this is very unusual at that level, and of course there are men with normal/low PSA who are metastatic.

User
Posted 03 Mar 2024 at 12:33

Thank you very much for that Andy.

 
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