Reduce Xtandi from 120 to 80?

My dh also takes 3 instead 4 due to headaches and feeling muzzy. He has thought of asking to take just the 2. But it’s the hot flushes causing the most problem. I don’t think reducing by one will reduce those as he’s on zoladex too. I read a report online about 2 groups of men on Xtandi one group took 2 tablets the other took 4 tablets. It goes on to say that the men in both groups averaged the same amount of time before the drugs became ineffective. I can’t remember how long ago or how long the trial was though. I’ll try to find it again sometime. 

Dh finds the hot flushes hard. He feels like he’s going to pass out. Some days he has 3 or 4. Other days they are every hour or so. 

He had a week off them a while ago to see if the headaches eased off. But a week didn’t make any difference. So he went back on the 3. 

I've been having hot flushes at 9 am and 9 pm, which are generally manageable. My oncologist says Zolodex prioritizes quality of life. Since Xtandi has a half-life of 5.4 days, I should notice any changes or adverse effects within a week.

https://community.prostatecanceruk.org/posts/m299304-geometry dash-Reduce-Xtandi-from-120-to-80

Edited by member 29 Aug 2024 at 11:19  | Reason: Not specified

Andy62 DH was given provera. He’s not taken them yet. He doesn’t like the look of the side effects like growing breasts. But also, as he has the brca gene we aren’t sure whether adding an extra hormone in is a good idea. It says on them if you have a history of breast cancer consult your gp. Obviously they are tablets for woman during menopause and the breast cancer is aimed at woman on the drug. But I’m sure a woman with the gene wouldn’t be prescribed them so I’ve no idea whether it’s the same for men. I suggested dh ask the nurse if they are safe to take. But as he can’t remember anything these days, he asked the nurse whether another tablet was safe instead, a tablet that has nothing to do with hormones. To which she said they are fine. So next nurse consult, I’ll write it down for him to ask.