Hi All,
I seem to have a problem on the day AFTER I take Alprostadil (40mcg. dose). I cannot get any kind of reaction from my penis. It appears to be "lifeless". Usually, I can get some kind of (modest) reaction by taking Sildenafil or Cialis, but NOT if I've taken Alprostadil the day before. I feel that this lack of response to PDE5i medication is limiting my options even further. I am only prescribed Alprostadil once weekly, so it seems like I have one throw of the dice every week. I can still use the vacuum pump, but I take low dose Cialis daily to enhance the effect of the pump, which usually helps, except if I've taken Alprostadil.
Has anyone else experienced this? There is no mention of this possible reaction on the Patient Information Leaflet. I've only been using Alprostadil 40mcg. for 2 months. Previously I was on a lower dose (for over a year), which was ineffective. Is it possible that this reaction is caused by scarring to the inside of the penis already?
Any information or opinions as to what might be the cause would be very welcome.
Many thanks.
JedSee.