I was due to start Enzalutamide alongside  digarelix injections. I had a starting PSA of 1356 and after 3 months on digarelix my PSA has risen to 1500, they are now saying I could be in the 2% of other cell cancer! I am  73 was diagnosed in April with mets to bones and lymph nodes around prostate area. 
It seems we are back to the drawing board and I  will now have a biopsy, they also said other rarer prostate cancer cells do not usually cause such a big increase in PSA so they are a bit confused which has unsettled me even more! 
Anyone had similar problems please and does anyone know what the new treatment path could be? 
Thank you in advance