Enzutamide after Aberaterone

Hello Annie,

The NHS won't pay for Enzalutamide (or Apalutamide or Daralutamide) after Abiraterone stops working. They say that when one of these stops working, the others won't work either.

Chemotherapy can be used again if it worked last time and the patient is well enough. There is also a second chemo drug which is sometimes used.

Hi Andy & Phil 

Thanks for the reply. He is on chemo at the moment. He had his 3rd cycle two week ago and is due his next one next week. But he was quite poorly with the last one and more concerning is,it seems to have affected his sight. 

We see his oncologist Monday so will see what she says. 

Thank you 😊

Edited by member 16 Jul 2024 at 10:12  | Reason: Not specified

Hi Andy,

Yes, he didn’t link it to the chemo at first and so optician arranged emergency eye appointment. They didn’t think it was a concern just an age thing. It was pretty mild at this time ( just after 1st cycle) but after the last one it got really bad so obviously he’s now very scared of losing sight in that eye and has since seen two more opticians.

We are seeing oncologist Monday so will see what she says. 

Morning Phil,

We have spoken about whether it could be a coincidence. He had a cataract removed from that eye last year and Optician said it can happen apparently with chemo. 
Trouble is whether it’s coincidence or not it’s scared the daylights out of him. 

The third cycle hit him quite bad with side effects although this time we kept the pain in his spine under control ( ended up in hospital with severe back pain after 1st cycle, they thought he had a spinal compression). Must have just been the cancer kicking back. 

I read your bio and followed your thread well done to your wife getting through 9 cycles 😊 good luck for your 10th.