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Tamsulosin side effects?

User
Posted 28 Aug 2024 at 10:51

Hi All,


Further to my recent post regarding the onset of late urinary cystitis/urethritis, my GP put me on Tamsulosin about 2 weeks ago.  In the last 3-4 days, my urinary frequeny seems to have got worse and this has been accompanied by slight urinary leakage.  I wonder if this is the Tamsulosin and if anyone else can relate to this?


Cheers.

User
Posted 28 Aug 2024 at 11:05

Tamsulosin helps you pee faster by relaxing the smooth muscle of the prostate and internal urinary sphincter. This is to help out in the situation where you are peeing slowly and not fully emptying your bladder, and hence going to the loo more often, or going in to retention (where you can't pee at all). Was that your situation? That's not what you're saying above were your symptoms, which makes me wonder why you were given Tamsulosin.


A side effect of relaxing the smooth muscle of the internal urinary sphincter is that you could become less continent, particularly if you have urgency, it can cause urge incontinence.


Side effects are reduced blood pressure, and retrograde ejaculation (because of weakened internal urinary sphincter).


Tamsulosin won't do anything useful if you have no prostate, as all the tissues it acts on have been removed.

User
Posted 29 Aug 2024 at 13:26

I've been on tamsulosin for 20 months now and I get the impression it's not as good as urology departments think it is.  It makes at best a marginal difference to my normal urine flow.   It didn't help when I had acute urine retention after HIFU, even if I took a double dose.  


It also seems to make me feel a bit sick and dizzy on getting out of bed in the morning.  I gather this is the reduced blood pressure side effect. 


Regarding urge incontinence (mentioned by Andy62)  I hadn't linked this to tamsulosin but come to think of it, I never had this symptom (as opposed to nocturia etc) before I was prescribed it.


 

User
Posted 29 Aug 2024 at 14:08

It might be worth asking to try an anti-bladder spasm medication, such as Solifenacin, Betmiga, or Trospium Chloride.

User
Posted 29 Aug 2024 at 23:17
I take tamsulosin along with solifenacin... the combination has definitely helped me to improve flow (had problems starting in particular) whilst reducing frequency (was going 5 times in a couple of hours sometimes) though obviously not everyone gets the same outcome so maybe I've been lucky in that respect; ive not had any noticeable side effects either.
User
Posted 04 Sep 2024 at 09:04
Don't think tamsulosin alters frequency hence why I had solifenacin added too. That combination works great for me.
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User
Posted 28 Aug 2024 at 11:05

Tamsulosin helps you pee faster by relaxing the smooth muscle of the prostate and internal urinary sphincter. This is to help out in the situation where you are peeing slowly and not fully emptying your bladder, and hence going to the loo more often, or going in to retention (where you can't pee at all). Was that your situation? That's not what you're saying above were your symptoms, which makes me wonder why you were given Tamsulosin.


A side effect of relaxing the smooth muscle of the internal urinary sphincter is that you could become less continent, particularly if you have urgency, it can cause urge incontinence.


Side effects are reduced blood pressure, and retrograde ejaculation (because of weakened internal urinary sphincter).


Tamsulosin won't do anything useful if you have no prostate, as all the tissues it acts on have been removed.

User
Posted 28 Aug 2024 at 11:41

Thanks Andy.


Still got a prostate - I had SBRT in April '23 (following 6 months of hormone therapy).


My late symptoms were (are) in descending order of impact on quality of life - frequency, dysuria, nocturia, urgency, hesitancy, intermittence & weak flow.  The last 3 were really no hassle but have improved with Tamsulosin.


The first GP I saw (in July) said he didn't think Tamsulosin would do much for me.  The second prescribed it (when I felt I had to try something...).  


The frequency feels like more of an issue than it was before Tamsulosin & the slight leakage is new.  I suppose the increased frequency could be due to the feeling of leakage...


Thanks again!

User
Posted 29 Aug 2024 at 13:26

I've been on tamsulosin for 20 months now and I get the impression it's not as good as urology departments think it is.  It makes at best a marginal difference to my normal urine flow.   It didn't help when I had acute urine retention after HIFU, even if I took a double dose.  


It also seems to make me feel a bit sick and dizzy on getting out of bed in the morning.  I gather this is the reduced blood pressure side effect. 


Regarding urge incontinence (mentioned by Andy62)  I hadn't linked this to tamsulosin but come to think of it, I never had this symptom (as opposed to nocturia etc) before I was prescribed it.


 

User
Posted 29 Aug 2024 at 14:08

It might be worth asking to try an anti-bladder spasm medication, such as Solifenacin, Betmiga, or Trospium Chloride.

User
Posted 29 Aug 2024 at 14:24

Thanks.  Been in touch with my oncologist & he's told me he's likely to refer me to a urologist.  I'll ask about these then.  


The last four days, I've peed on average 18 times a day - which, I'm sure, is up on where I was pre-Tamsulosin.  I didn't take the Tamsulosin this morning and I think I'll stay off it (as I really didn't have an issue with flow).  I'll report back if the frequency and leakage issues improve...

User
Posted 29 Aug 2024 at 23:17
I take tamsulosin along with solifenacin... the combination has definitely helped me to improve flow (had problems starting in particular) whilst reducing frequency (was going 5 times in a couple of hours sometimes) though obviously not everyone gets the same outcome so maybe I've been lucky in that respect; ive not had any noticeable side effects either.
User
Posted 03 Sep 2024 at 11:16

An update.  So I stopped taking Tamsulosin 6 days ago.  My flow issues have returned (slow to start, intermittent & weakish flow) - but I can live with them.  So the Tamsulosin clearly works for me in this area.  Frequency is still an issue - so if Tamsulosin altered that, it was marginal.  The slight leakage I experienced has gone & I think that had contributed to the feeling of increased frequency.  So, for me, the benefit of the relaxed muscles was outweighed by the leakage & feeling of increased frequency.

User
Posted 04 Sep 2024 at 09:04
Don't think tamsulosin alters frequency hence why I had solifenacin added too. That combination works great for me.
 
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