PSA 15 months after prostatectomy

User

Posted 04 Nov 2024 at 20:41

So I had a radical prostatectomy in July 2023 with routine PSA follow ups, all coming in at <0.01 except for the latest one which was 0.01 (ie: without the magic '<' sign)

My post op histology was Gleason 3+4=7, T2c N0 (0/6), clear margins.

Been feeling quietly confident tbh, but latest PSA is a bit of an unwelcome surprise, not a massive jump obviously but a bit concerning. Is this the start of an upward trend or an anomaly / blip?

My CNS thinks things should be in my favour with my scores, clear margins etc and isn't unduly concerned. However, I flip between fearing the worst and telling myself it'll all be fine. Next PSA will be in January.

Does anyone have any thoughts, experience or other insights in this area?

User

Posted 04 Nov 2024 at 22:05

Hi John.

You state that your latest PSA was 0.01 unlike the others that were <0.01. Are you sure it isn't a typo and they've just missed off the <. It seems a remarkable coincidence, apart from the < , that your scores are exactly the same.

I had the op 21 months ago, my laboratory only measures down to 0.02.

I don't think you've got anything to worry about mate.

Keep getting your PSA tests. I think they class possible recurrence as 0.2 and you're a long way from that.

Edited by member 04 Nov 2024 at 22:13 | Reason: Typo

User

Posted 05 Nov 2024 at 12:18

Measuring down to 0.01 is lower than incredibly low. There is much said about psa levels and I've read that below 0.03 it's not very accurate, I've also read that if it's measured as lower than 0.01 then that's almost as perfect a result as you're ever likely to get and the likelihood of a recurrance is very low indeed. Many hospitals measure down to 0.1 which is 10 times more than yours.

Edited by member 05 Nov 2024 at 12:19 | Reason: Not specified

User

Posted 05 Nov 2024 at 15:54

Hi John

My diagnosis following biopsy was overall Gleason 3+4, T3a N0 M0 prostate cancer with presenting PSA of 17. All biopsies positive for prostate cancer with target lesions showing Gleason 4+3.

RARP performed on 02.08.2024.

The one month follow up pathology report post RARP showed negative margins.

My first PSA result post RARP on 18.10 was 0.02.

During the second post op phone consultation with the surgeon on 29.10 he said he was very pleased with the PSA result as anything below 0.03 was good.

I reckon you are doing well and as long as the PSA levels remain at this level you have nothing to worry about.

Hope this helps.

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User

Posted 04 Nov 2024 at 22:05

Hi John.

I had the op 21 months ago, my laboratory only measures down to 0.02.

I don't think you've got anything to worry about mate.

Keep getting your PSA tests. I think they class possible recurrence as 0.2 and you're a long way from that.

Edited by member 04 Nov 2024 at 22:13 | Reason: Typo

User

Posted 05 Nov 2024 at 12:18

Edited by member 05 Nov 2024 at 12:19 | Reason: Not specified

User

Posted 05 Nov 2024 at 15:54

Hi John

My diagnosis following biopsy was overall Gleason 3+4, T3a N0 M0 prostate cancer with presenting PSA of 17. All biopsies positive for prostate cancer with target lesions showing Gleason 4+3.

RARP performed on 02.08.2024.

The one month follow up pathology report post RARP showed negative margins.

My first PSA result post RARP on 18.10 was 0.02.

During the second post op phone consultation with the surgeon on 29.10 he said he was very pleased with the PSA result as anything below 0.03 was good.

I reckon you are doing well and as long as the PSA levels remain at this level you have nothing to worry about.

Hope this helps.

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