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Reoccurance after RT

User
Posted 17 Dec 2024 at 11:31

I am very new to all this, having finished Radio Therapy along with T-Blockers in November 2023. I was told my PSA should drop to a very low level but with RT there may be a bounce. In March 2024 my PSA was 0.089, June - 0.55, September 0.683, and December - 1.1

This looks like a ramp to me rather than a bounce, increasing by 0.4 every three months it looks like I will be up to the threshold of 2 in 6 months where further investigation is deemed necessary.

On the positive side, I was diagnosed with stage 2, 1 core of 17 showing positive, but Gleeson score of 7. Due to chronic lower back pain I had a bone scan in October which showed nothing worrying.

My question is, is my PSA typical? My Oncologist at my last phone meeting said it was due to the Testosterone levels recovering. But previously my understanding was that Radio Therapy was supposed to reduce the PSA count.

I would appreciate any thoughts or information.

User
Posted 17 Dec 2024 at 12:38

When did you start and finish HT? What was your PSA at diagnosis?

It is quite reasonable that your remaining prostate cells will be producing PSA at their normal rate, and a PSA of 1 or 2 is not unreasonable for a healthy prostate in a 66 year old.

If your PSA remained very low that would be clear evidence that you do not have a problem. Your current PSA is NOT evidence that you do have a problem. You will just have to wait and see.

Dave

User
Posted 22 Dec 2024 at 21:04
I think my HT finished just prior to the start of RT, so October 2024. 20 shots of external beam RT in November.

I have heard that cycling might raise one's PSA. I have cycled to my 3 monthly blood tests, about 4 miles. Maybe this is giving me an increased score?

User
Posted 23 Dec 2024 at 15:25

I’m no expert on cycling or even PCa but I’ve definitely heard do not cycle before a PSA test. Don’t know the likely amount it could affect it by though. Presumably someone will come on with better knowledge soon. 

Phil

User
Posted 23 Dec 2024 at 16:39
I do not believe the cycling phenomenon is relevant for men post radical treatment.

The threshold post RT is Nadir +2 so you will be considered to have failed treatment at 2.089.

 
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