Start of rollercoaster

Hello all

Been a year since last on here, so the update is:

The three monthly PSA tests over the last 12months have averaged in the mid to high 7's. A follow up mpMRI in July showed PIRADS1/2 and T1c and no visible lesions or tumor - exactly the same as the previous year - and gives lots of comfort that nothing is progressing. Interestingly the initial bi-parametric MRI in 2024 showed PIRADS 4 and T2 - clearly the multi-parametric MRI has a more granular and accurate focus. 

There's the odd PSA blip up - last weeks test was 8.8 - that did cause initial worry but having cross referenced PSA dates to detailed cycling activity a pattern is starting to emerge that significant offroad treks (I recently cycled Glasgow to Inverness offroad = 220 miles & 19,000ft climb over bumpy mountain trails) is likely causing these PSA spikes, and probably mild BPH. Previously I left it 3 or 4 days before a test but from now on I will refrain from cycling at least a week, and nearer 2 weeks from any long distance offroad treks, and see what the PSA test returns then. Interestingly I read on the internet that the half life of PSA is 2 to 3 days - so that takes circa 2 weeks to get to 2% above a baseline. 

Given the static mpMRI results, the Urologist is generally happy but has put a limit of PSAD (ratio of PSA to prostate volume) at 0.25 - it's generally hanging around the 0.2 mark - before thinking about another biopsy. 

Still taking the YourPhyto bio & gut microbe pills twice daily, lots of cycling (4000+ miles YTD) and watching the diet with virtually no processed foods, cut out all pork & chicken and only the occasional organic beef, lamb or venison meal. Sugars restricted to fruit & honey. Lots of tomatoes, veg, whole grains, nuts & pulses, milk only in tea, yogurt on homemade muesli, and lots more fish. Beers and wine - well, that's work in progress ;-)

So, active surveillance continues and as time goes on I'm getting more comfortable with it all as longer term data & trends emerge. The need for interventions that previously worried me seem less likely for at least the immediate and hopefully medium/long term future too.

Cheers for now

Gi

Edited by member 07 Oct 2026 at 00:25  | Reason: Not specified

Hi there and I hope your stay will be a short one.

I had very similar numbers to you and had to have a biopsy.

That was transrectal, which was absolutely no problem at all. Don't get anxious about it at all, it's a breeze, if a bit undignified.

My results didn't come back quickly and I chased them up just before Christmas. 

A secretary told me I'd been discharged, without any explanation or advice. The discharge letter was equally bland.

I did get to talk to a nurse who said I would be referred back to my GP and would probably be tested with a higher baseline PSA threshold. 

So a lot of worry and stress was popped like a balloon in one phone call.

I hope you have the same result and can get back to a normal life.

Best regards, mick. 

Thanks for the update, mate. No a bad result at all, you appear to be an ideal candidate for active surveillance. I hope your Gleason 6 is a pussy cat and that you never need any further treatment.

Best of luck pal. 👍