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User

Posted 11 Jan 2025 at 12:13

Hello all. New here and trying to find info & advice.

Im 58 and at last October MoT had a PSA test = 4.8. (Previous was 2.7 3 years ago). Was fairly relaxed as cycle off road about 60 miles a week so thought it was bumping about on Scottish hills. Did a follow up 3 weeks later & without any cycling for a week and it was 5.7. That got me worried. Got an MRI scan and results just in that I'm in 4 to 5 range but with no peripheral signs of abnormality. Next step is Biopsy I guess which I'm not looking forward to!

Wonder if I should take another PSA test before a biopsy to give a baseline as biopsy likely to spike it afterwards?

Is there anything else I should be doing and/or asking at this stage? From what I read on MRI results a 4 is likely a 70% or more, and a 5 90+% chance of C?

Kinda still hoping that an op 2 years ago for urethral stricture (with catheter etc) and/or bouncing about on my gravel bike has caused these MRI results.......but I'm keen to not bury head in the sand so biopsy it is.

User

Posted 11 Jan 2025 at 15:46

Hello mate.

Sorry to see that you've had to join the Club, but welcome to the forum.

The MRI 4 and 5 means likely and very likely to have prostate cancer but I shouldn't worry too much about that. Your PSA is relatively low and can be caused by other prostate conditions.

A biopsy will show more accurately if you have cancer and how aggressive it is. We've had blokes with MRI scans of 4 and 5 and biopsies showed benign tumours.

The biopsy is nothing to worry about, most would describe it as a bit uncomfortable.

Good luck and please keep us updated. Whatever your results we will be here, if required, to help and support you. 👍

User

Posted 11 Jan 2025 at 17:27

Hi there and I hope your stay will be a short one.

I had very similar numbers to you and had to have a biopsy.

That was transrectal, which was absolutely no problem at all. Don't get anxious about it at all, it's a breeze, if a bit undignified.

My results didn't come back quickly and I chased them up just before Christmas.

A secretary told me I'd been discharged, without any explanation or advice. The discharge letter was equally bland.

I did get to talk to a nurse who said I would be referred back to my GP and would probably be tested with a higher baseline PSA threshold.

So a lot of worry and stress was popped like a balloon in one phone call.

I hope you have the same result and can get back to a normal life.

Best regards, mick.

User

Posted 12 Jan 2025 at 00:08

There are a lot of cyclists here on the forum and there's a suspicion of a connection between cycling and prostate cancer but so far as I know no link has been found.

If you're going for a psa test, the results can be temporarily raised by some activities so I'd suggest you stay off your bike for 24hr prior to the test and standardize your test time and conditions as much as possible to avoid messing with the results.

Jules

User

Posted 21 Feb 2025 at 20:51

Thanks for the update, mate. No a bad result at all, you appear to be an ideal candidate for active surveillance. I hope your Gleason 6 is a pussy cat and that you never need any further treatment.

Best of luck pal. 👍

User

Posted 22 Feb 2025 at 00:11

Originally Posted by: Online Community Member

Anything else I should be doing and/or thinking about?

Exercise, good diet and regular testing, you're doing brilliantly!

Jules

User

Posted 22 Feb 2025 at 11:10

Hi Gi

You seem to have a good plan in place and as others have said, keep being monitored regularly.

I don't know if this is of any interest, but I started taking these 2 supplements after reading about "The UK YourPhyto Scientific Study" - combining a probiotic supplement and a new generation phytochemical rich food capsule to aid men with indolent prostate cancer. A double blind Randomised Placebo Controlled Trial.

See the link below.

https://yourphyto.com/scientific-study

Wishing you well.

Seb

User

Posted 08 Aug 2025 at 22:18

Gi58,

Thanks for the comprehensive update. Your fluctuating PSA is a bit of a mystery but nice to see this trend is now downwards. I'd be more than happy to follow your latest monitoring plan and have another couple of PSA tests before considering further treatment.

Best of luck, mate.👍

Show Most Thanked Posts

User

Posted 11 Jan 2025 at 15:46

Hello mate.

Sorry to see that you've had to join the Club, but welcome to the forum.

The MRI 4 and 5 means likely and very likely to have prostate cancer but I shouldn't worry too much about that. Your PSA is relatively low and can be caused by other prostate conditions.

A biopsy will show more accurately if you have cancer and how aggressive it is. We've had blokes with MRI scans of 4 and 5 and biopsies showed benign tumours.

The biopsy is nothing to worry about, most would describe it as a bit uncomfortable.

Good luck and please keep us updated. Whatever your results we will be here, if required, to help and support you. 👍

User

Posted 11 Jan 2025 at 17:27

Hi there and I hope your stay will be a short one.

I had very similar numbers to you and had to have a biopsy.

That was transrectal, which was absolutely no problem at all. Don't get anxious about it at all, it's a breeze, if a bit undignified.

My results didn't come back quickly and I chased them up just before Christmas.

A secretary told me I'd been discharged, without any explanation or advice. The discharge letter was equally bland.

I did get to talk to a nurse who said I would be referred back to my GP and would probably be tested with a higher baseline PSA threshold.

So a lot of worry and stress was popped like a balloon in one phone call.

I hope you have the same result and can get back to a normal life.

Best regards, mick.

User

Posted 12 Jan 2025 at 00:08

There are a lot of cyclists here on the forum and there's a suspicion of a connection between cycling and prostate cancer but so far as I know no link has been found.

Jules

User

Posted 17 Jan 2025 at 18:09

Thanks guys. Biopsy due next week, under full anaesthetic. Fingers crossed!

Meantime I'm off the bike and piling on the lbs.

Edited by member 17 Jan 2025 at 18:11 | Reason: Not specified

User

Posted 21 Feb 2025 at 20:02

Post biopsy update = Gleason 6 (3+3) & between T1 and T2a on one side only. Latest PSA 6.6

Urologist suggests watching brief with 6 month PSA tests and annual MRI.

I guess if it was going to be cancer then this is as good a result as it gets. But remain concerned it may grow quicker and outside the prostate.

Anyhow going to tweak the diet to include more fresh fruit & veg, pomegranate green tea and get back on the gravel bike to train for a 240 mile trek over 4 days in May and a 100 miler overnight on the summer solstice.

Anything else I should be doing and/or thinking about?

Thanks again

User

Posted 21 Feb 2025 at 20:51

Thanks for the update, mate. No a bad result at all, you appear to be an ideal candidate for active surveillance. I hope your Gleason 6 is a pussy cat and that you never need any further treatment.

Best of luck pal. 👍

User

Posted 22 Feb 2025 at 00:11

Originally Posted by: Online Community Member

Anything else I should be doing and/or thinking about?

Exercise, good diet and regular testing, you're doing brilliantly!

Jules

User

Posted 22 Feb 2025 at 08:51

Originally Posted by: Online Community Member

Anything else I should be doing and/or thinking about?

Exercise, good diet and regular testing, you're doing brilliantly!

Jules

Thanks Jules! Yep - my GF has a 'life extension plan' for me already 😉

User

Posted 22 Feb 2025 at 08:53

Originally Posted by: Online Community Member

Thanks for the update, mate. No a bad result at all, you appear to be an ideal candidate for active surveillance. I hope your Gleason 6 is a pussy cat and that you never need any further treatment.

Best of luck pal. 👍

Thanks Adrian! 🙂

User

Posted 22 Feb 2025 at 11:10

Hi Gi

You seem to have a good plan in place and as others have said, keep being monitored regularly.

See the link below.

https://yourphyto.com/scientific-study

Wishing you well.

Seb

User

Posted 23 Feb 2025 at 12:53

Originally Posted by: Online Community Member

Hi Gi

You seem to have a good plan in place and as others have said, keep being monitored regularly.

I don't know if this is of any interest, but I started taking these 2 supplements after reading about "The UK YourPhyto Scientific Study" - combining a probiotic supplement and a new generation phytochemical rich food capsule to aid men with indolent prostate cancer. A double blind Randomised Placebo Controlled Trial.

See the link below.

https://yourphyto.com/scientific-study

Wishing you well.

Seb

Thanks Seb!

Really interesting topic and data there - and something will definately read up more.

I did the Zoe test 18 months ago which highlighted gut health and reducing processed foods. Since then have lost 6kg, boosted my good cholesterol and also put on muscle mass in legs from cycling 50+ miles a week.

But there's still more to do with the diet and adding supplements too.

Thanks again

User

Posted 08 Aug 2025 at 21:51

Hi all

A recap and update:

PSA 4.8 last October, 5.6 in November, 6.6 in Feb at time of Biopsy.

MRI: PIRADS 4; 37cc; PSAd 0.18 given 6.6 PSA; low diffuse T2 one side; no focal lesions; no other abnormalities / findings outside the prostate.

Biopsy results: Gleason 6 (3+3); T2 no MX (was told T2a but that's not stated in the report); 4 cores positive in left lobe accounting for 20% tissue examined; Perineural invasion present.

In May the PSA test went to 8.4 - on a graphed trajectory akin to an Elon Musk 'salute' - neither being at all acceptable!

I had a urine test that showed no infection and was conscious of not cycling or sex 5+ days before the blood test.

In June I went to see a new specialist in Edinburgh recommended to me and he was rather concerned at the PSA rise and the PSAd now at 0.22 - and above a threshold of 0.2 that he uses as a parameter for safe surveillance.

Further multi-parametric MRI in July showed: prostate volume of 31cc. Within the prostate there is some patchy change in the peripheral zones on both sides but no obvious lesion as such. Therefore, at present the tumour is not visible on this MRI scan.

PSA taken mid July has dropped back to 6.2 - great news! Maybe the Your Phyto & Your Gut+ pills plus cutting out dairy & sugars, upping the good foods and exercise are having an effect?

However with a revised PSAd still hovering around 0.2 the recommendation is at least one and possibly two further PSA tests at three month intervals, to get an understanding of PSA trends. If it is upwards, and in view of the perineural invasion, then the specialists recommendation is a low threshold for moving to treatment. If, on the other hand, it continues to drop, then continue with active surveillance in the knowledge that the recent MRI scan did not show any visible disease, which makes the probability of their being significant grade 4 cancer present, quite low.

So there we are - teetering on the edge of intervention. If it is to be treatment am 'favouring' RP at the moment, but have not yet spoken to an Oncologist about other potential options. Given I’m not yet 60 (and hope I've got 20+ years ahead of me), probably fitter than average for my age and thinking to save chemo / rad for any future reoccurrence then the RP is a good roll of the dice I guess, but the post op physical effects are quite frankly really worrying me.

User

Posted 08 Aug 2025 at 22:18

Gi58,

Best of luck, mate.👍

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