I cycled pretty much every day during radiotherapy. I was doing this as far as possible all during my hormone therapy to reduce the hormone therapy side effects, although I'd been a cyclist for a couple of decades at that point, so it wasn't something I just started.
Only afterwards did I discover that exercising during radiotherapy improves radiotherapy outcomes. Radiotherapy works best when tissues are well oxygenated.
I did buy a noseless saddle, so there was no way to sit on my perineum. It only has a seat (which is well padded) under your sit-bones (pelvis), so you can't sit on the penile bulb, which is what causes ED for lots of cyclists (even with saddles which have an indentation there). I still use these today, years after my treatment. They do take a few rides to get used to and adjusted correctly. It looks like this, although I bought mine on Amazon, but the Amazon price has rocketed since then.