Hi everyone,
I’m looking for some positive news/rays of hope this evening. My Dad (a very young and fit 70yr old) was diagnosed Dec ’23 with T3a N0 M1, with mets to the bones. The Urologist advised it was Gleason score 10.
Initial treatment was apalutamide, the oncologist was not supportive of triplet therapy at the time. This did reduce the PSA for a few months, but not ever below 4, and then it started to rise. Repeat bone scans showed disease progression of existing mets and few areas. He had x6 cycles of Docetaxel and again the PSA decreased, but very slowly and not significantly and it then rapidly started to rise from cycle 4. The oncologist has stopped chemo now as it’s obviously failed.
I had to ask about Olaparib, which the oncologist agreed to test for, but didn’t think he’d have the BRCA gene due to how the cancer was behaving etc. I’ve since been doing my own research and wanted to know if anyone had had a good result from Cabazitaxel when Docetaxel has failed?
I’ve also been looking into the Enhertu trial and wanted to know if anyone has experience of this?
Trying to be positive, but the oncologist was very clear the cancer was aggressive and he wasn’t giving us much hope.