Hi David
I am just at the end of 2 years of Hormone therapy. Prostap 11.25mg injection every 12 weeks. My last jab (ever I hope) was in February 2025.
Good news - my cancer (which was high risk, 4+4 Gleason 8 and TB3N0M0) is under control at the moment (also had 20 sessions of EBRT at the begining of 2024)
Not so good news - I would feel worse for a week or so after each injection. As time went on the side effects also generally became more difficult to manage and were more severe (for me that included fatigue, flushes, joint pain, the sexual stuff (no libido/ED) and muscle pain.
I am not yet benefitting hugely from stopping the medication but flushes are a little less fierce, energy seems a little recovered and just about to start some exercise rehabilitation. The worse for me, which has not recovered at all as yet - is joint pain.
I worked full time all through my treatment (not a wise choice but I bet a lot of us do it) During my second year of treatment i would arrange for my injection to be late afternoon and take a day or two leave after the injection - and that helped. I was also lucky to have a supportive employer who lets me (still) take time away when my fatigue gets too much - eg the odd hour or sometimes half day. I found that really helped - both because I wasn't worrying all day what i would do if my energy faltered, but also to allow me to look after myself a little better.
I hope some of the above helps you with your situation, even if it is just that you are not alone at having more intense side effects straight after an injection.
Good luck, mate - I hope your recovery goes well.
And thanks for bumping Adrian56 - I did wonder if I was imagining the injection effect and seeing this post makes me feel a bit better.