Elevated PSA After Biopsy

Email this conversation Print this conversation

User

Posted 21 Jun 2025 at 12:53

Hi, I had a mpMRI which showed PIRAD score of 3 and possible 4s. I opted for a biopsy which revealed a Gleason score of 3+3. I developed a blot clot on each lung after the op resulting in me now being on blood thinners.

10 weeks after the biopsy I had a further PSA test which has come back at 4.3, when prior it was 2.7. I'm 49, family history of PC. From what I've read, my PSA level should have dropped back to my previous score. I'm yet to speak to my urologist as it's the weekend. Could anyone offer some thoughts as to why it's not returned yet? Thanks.

User

Posted 21 Jun 2025 at 17:08

Hi Dave.

I'm sorry that you've had to join the club, but welcome to the forum, mate.

I'm not medically trained, but your PSA levels, pre and post biopsy, are slightly above normal, but not particularly high, neither is your Gleason score. Your MRI scan shows an intermediate chance of clinically significant cancer.

Please view this video on Gleason 6(3+3).

https://youtu.be/a0sjUallZQU?si=lMLdMJ3PxV5GA_uX

Why did you have an initial PSA check? Was it precautionary, as you have a family history of PCa, or was it for some other reason?

PSA levels can rise due to non cancerous prostate conditions and other infections etc. Biopsies themselves can also cause a rise in PSA but it's usually stabilised to previous levels after 10 weeks.

Are the blood clots on your lungs connected to your biopsy?

Speak with your urologist, mate, and hopefully he/she will put your mind at rest.

Good luck mate.👍

Edited by member 21 Jun 2025 at 17:19 | Reason: Typo

User

Posted 23 Jun 2025 at 22:02

Thanks Adrian,

I guess I went looking to confirm one way or another as my Dad died from it 5 years ago. He never shared much about his details. I'm off to see a haematologist to discuss the clots, but being within 2 weeks of the biopsy, it's quite possible. I'm currently waiting for a reply from my urologist.

Email this conversation Print this conversation

Join the online community now.

Click through to become a member and gain access to support, information and real time replies.