Bicalutamide 50mg 2 months prior to surgery

User

Posted 28 Jun 2025 at 16:49

Hi All,

My first post here since being diagnosed with T2C in May.

After a lot of deliberation and conversations with the medical experts I've decided to go with surgery and will almost certainly being treated privately as my surgeon was proposing a non-nerve sparing operation whereas the new London Prof thinks he can do better with NeuroSAFE. I've been prescribed 2 months of Bicalutamide prior to the operation and am keen to know what side effects people have experienced at this level. Obviously, I understand that everyone reacts differently to these treatments.

Thanks

Nick

User

Posted 11 Sep 2025 at 07:28

Well the catheter was removed yesterday (hurrah!) and at the moment, fingers crossed, I'm leak free. Hopefully things will continue on the same path!

Nick.

User

Posted 02 Sep 2025 at 15:07

Ahoy! Wingers.

Thanks & good luck going under the knife tomorrow.

All the best,
Taps.

Edited by member 02 Sep 2025 at 15:45 | Reason: Not specified

User

Posted 02 Sep 2025 at 17:04

All the best for tomorrow mate

don't do what I did when you wake up and ask them how long it will be before they do it :) , I was eating ice cream a few hours later

Nick

User

Posted 02 Sep 2025 at 17:21

Hi Nick,

Thanks very much. Not really a day I've been looking forward to, but it'll be nice to get it over with!

That sounds like a good way to experience an Op - I look forward to the ice cream!

Nick.

User

Posted 07 Sep 2025 at 16:21

Glad your on the other side of it Nick , I really wasn’t a fan of the catheter either , suggest for the trip home , couple of soft pillows ,one to sit on and one to stop the seatbelt rubbing the wound , also hospital gave me a wide rimmed plastic bottle incase your desperate and can’t stop if your on the motorway etc, a rug would come in handy if that happens as well.

all the best mate

Nick

User

Posted 09 Sep 2025 at 10:51

I was pleasantly surprised after mine was taken out , the odd drip but that’s it , fingers crossed for the same for you 👍🤞

User

Posted 11 Sep 2025 at 09:03

Great news Nick , all the best going forward

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User

Posted 29 Jun 2025 at 08:15

I was on Bicalutamide for 3 months prior to Radiotherapy only issue I had was it lowered my blood pressure in the morning as I take blood pressure medication, I was advised to take the Bicalutamide at night and that helped regulate my blood pressure, only other advise I could give is to exercise regularly as it does make you feel tired,hope all goes well

John

User

Posted 29 Jun 2025 at 12:55

Hi John,

Thanks very much for your reply - it's really good to hear from people who have actual experience of medication and treatment and it gives me some more hope that things may not be too bad,

Hope you're doing well.

Thanks

Nick.

Edited by member 29 Jun 2025 at 21:18 | Reason: Spelling mistake

User

Posted 29 Jun 2025 at 13:59

Hi Nick.

Im sorry youve had to join our club, but welcome to the forum, mate. You'll get lots of help and support here.

I was on Bical for 2 months prior to RARP. I got sore and swollen nipples, that took about 3 months to return to normal after the medication stopped.

Good luck with your treatment. 👍

Edited by member 29 Jun 2025 at 14:13 | Reason: Additional text

User

Posted 29 Jun 2025 at 17:15

Hi Adrianus,

Thanks very much for the welcome.

Thanks for the info your symptoms sound as if they were uncomfortable but not dreadful (hopefully not worse than I'm imagining!). I'll bear that one in mind.

Hope you're doing ok now.

Nick.

User

Posted 29 Jun 2025 at 20:38

Nick , I went on 150mg of Bicalutamide for six months, similar side effects, sore and swollen nipples, mine have probably reduced slightly. Perhaps a slight drop in labido. Hope all goes well for you.

Thanks Chris

User

Posted 30 Jun 2025 at 07:58

Thanks Chris,

Thank's for your thoughts, thay are very helpful. There definitely seems to be a pattern here and one that I will now at least be expecting. I'll be starting my course of Bicalutamide tomorrow so we'll see what happens.

Thanks

Nick.

Edited by member 30 Jun 2025 at 13:23 | Reason: Not specified

User

Posted 04 Aug 2025 at 16:54

Just a quick update:

One month in and I don't really seem to be experiencing any side effects and am hoping that will remain the case for the final month. Then the operation!

Thanks

Nick.

Edited by member 04 Aug 2025 at 16:55 | Reason: Not specified

User

Posted 02 Sep 2025 at 08:15

I took Bicalutamide 2 weeks before my first Prostap3 injection, & for two weeks after. I don't think I had any effects from the B as I had the P3 injection so soon afterwards. The P3 effects are another story. I started a 35 session of RT about 2 months later.

I have been "walnutless" since Nov '23 & had to go on RT/HT due to a tiny amount of the PC was caught on a PET scan due to a slight rise in my PSA. PSA is now <0.025. Got my 3 monthly PSA test today so my nerves are a bit jangly.

User

Posted 02 Sep 2025 at 14:42

Hi Taps,

Good luck with the PSA test - hopefully it'll effectively be 0.

I'm due for my Op tomorrow so I can fully understand jangly nerve syndrome!

I've just finished my course of Bicalutamide (2 months) and didn't really experience any side effects so I'm just hoping my concerns over the operation are also unfounded!

Good luck

Nick.

User

Posted 02 Sep 2025 at 15:07

Ahoy! Wingers.

Thanks & good luck going under the knife tomorrow.

All the best,
Taps.

Edited by member 02 Sep 2025 at 15:45 | Reason: Not specified

User

Posted 02 Sep 2025 at 17:04

All the best for tomorrow mate

don't do what I did when you wake up and ask them how long it will be before they do it :) , I was eating ice cream a few hours later

Nick

User

Posted 02 Sep 2025 at 17:21

Hi Nick,

Thanks very much. Not really a day I've been looking forward to, but it'll be nice to get it over with!

That sounds like a good way to experience an Op - I look forward to the ice cream!

Nick.

User

Posted 02 Sep 2025 at 17:23

Thanks very much Taps, looking forward to being on the other side of the Op!

Thanks

Nick.

User

Posted 03 Sep 2025 at 08:17

You won't know owt about it once you've had a few lungful's of "gas"!
And don't be too alarmed about the garden-hose hanging out of your todger. :-)

Edit: Get yourself a few good books. You won't be doing much but resting. What you'll go through for the next couple of months will hopefully be nothing out of the ordinary. Most here have been through it & have a wealth of advice, and reassurance, should you need it.

All the best,

T14

Edited by member 03 Sep 2025 at 08:49 | Reason: Not specified

User

Posted 07 Sep 2025 at 08:33

Hi Taps,

Thanks for your thoughts. I'm on the other side of the Op now and of course you were right, the only part of this whole process that you know nothing about, or actually feel, is the operation!

I seem to be doing well, a bit sore (it hurts when I laugh ir cough) and I'm definitely not too keen on the catheter but that is due to be removed on Wednesday at which point I'll find out how leak proof I'll be for the 3 hour journey home!

Regards

Nick.

User

Posted 07 Sep 2025 at 16:21

all the best mate

Nick

User

Posted 09 Sep 2025 at 09:28

Hi Nick,

Thanks for the advice - I'll definitely be packing a couple of extra pillows and a wide rimmed container in preparation for the trip home. I already have a waterproof seat cover for my passenger seat as I'd rather make sure that stays dry!

I'm still hoping that it'll all be fine - but I'll find out tomorrow!

Regards

Nick.

Edited by member 09 Sep 2025 at 09:29 | Reason: Not specified

User

Posted 09 Sep 2025 at 10:51

I was pleasantly surprised after mine was taken out , the odd drip but that’s it , fingers crossed for the same for you 👍🤞

User

Posted 11 Sep 2025 at 07:28

Well the catheter was removed yesterday (hurrah!) and at the moment, fingers crossed, I'm leak free. Hopefully things will continue on the same path!

Nick.

User

Posted 11 Sep 2025 at 09:03

Great news Nick , all the best going forward

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