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Help with mri results

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User
Posted 18 Jul 2025 at 19:10

Hi,

Newbie here, concerned about below,

Can anyone decipher please,

Thanks.....

 

 

MRI Prostate with contrast Clinical indication : PSA 8.9 PDC M TEAM TO CONTACT 3T study. T1-weighted post-biopsy change: Nil Prostate size: 41cc. T2-weighted and Diffusion-weighted imaging findings: Within the left mid/base posterior PZ (8p/10p) there is a 12 x 11 mm low T2WI SI lesion with restricted diffusion and early enhancement, of M5 probability (s4i18, s550i18). There is an additional 12 x 8mm more wedge shaped region of low T2WI SI within the right apex PZ (6p), which shows milder restricted diffusion but also early enhancement, of M4 probability (s4i20, s550i20). A 5 x 4 mm ill defined focus of low T2WI SI within the right mid PZ (4a) has moderate restricted diffusion but no early enhancement, M4 probability (s4i16, s550i16). DCE-MRI findings: As above. Extra-capsular extension: No Seminal vesicle invasion: No Bone lesions: No Lymph nodes: None enlarged Impression: 12 x 11 mm M5 target left mid/base PZ (8p/10p) 12 x 7 mm M4 target right apex PZ (6p) 5 x 4 mm M4 target right mid PZ (4a)

User
Posted 18 Jul 2025 at 22:28

There's a lot of information there in a very abbreviated form. I recognise some of the words. BTW 3T, T1 and T2 have nothing to do with tumor staging, but something to do with magnets in an MRI. PZ means peripheral zone, but whether that is good or bad I have no idea. M5 and M4 probability is probably the likert scale from 1 to 5 but why it is not L4 and L5 I don't know. A score of Likert 5 means very high chance it is cancer. M team is probably multi disciplinary team, and if they are contacting you it means there is something to investigate.

So all the above paragraph is telling you what I can't really make sense of from this report.

What I can make sense of is:

PSA 8.9 which is high enough to justify an MRI.

Mention of lesions 5x4mm, 12x8, 12x11. And probabilities of 4 and 5 which I assume are high.

So probably cancer.

No Extra capsular extension, bone lesions or lymph nodes. Which means the probable cancer is probably all safely contained in the prostate.

At the moment no one knows if you have cancer, but you have enough lesions to justify a biopsy, only then will anyone know if you have cancer.

The fact there is nothing suspicious outside of your prostate means that if this is prostate cancer you will almost certainly be 100% curable.

 

Dave

User
Posted 19 Jul 2025 at 18:24

I had two pirads 4 scoring lesions on my mri scan which wre malteser sized.

I thought that was definitely going to be bad news at biopsy, but there was no sign of cancer.

It is definitely good advice to take this journey one test at a time. Wait for the results and move forward.

Good luck on the biopsy, stay positive above all else.

Mick 

User
Posted 18 Jul 2025 at 23:06

Hi Michael 

I'm sorry that you've got prostate problems, but welcome to the forum, mate.

I agree with Dave's summation.

The MRI warrants further investigation. You'll probably have a biopsy and the suspicious areas will be targeted to check whether or not they are cancerous and if they are, how aggressive they are likely to be.

Almost 18% of pi rads 4 and 5 lesions (high and very high likely to be clinically significant cancer) turn out to be benign. 

You're bound to be concerned and confused, most of us were. Just take one procedure and one set of results at a time. If you end up being diagnosed with prostate cancer, you'll be given treatment options which you can then focus on.

You'll find lots of help and support here. Please keep us updated and good luck. 👍

 

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User
Posted 18 Jul 2025 at 22:28

There's a lot of information there in a very abbreviated form. I recognise some of the words. BTW 3T, T1 and T2 have nothing to do with tumor staging, but something to do with magnets in an MRI. PZ means peripheral zone, but whether that is good or bad I have no idea. M5 and M4 probability is probably the likert scale from 1 to 5 but why it is not L4 and L5 I don't know. A score of Likert 5 means very high chance it is cancer. M team is probably multi disciplinary team, and if they are contacting you it means there is something to investigate.

So all the above paragraph is telling you what I can't really make sense of from this report.

What I can make sense of is:

PSA 8.9 which is high enough to justify an MRI.

Mention of lesions 5x4mm, 12x8, 12x11. And probabilities of 4 and 5 which I assume are high.

So probably cancer.

No Extra capsular extension, bone lesions or lymph nodes. Which means the probable cancer is probably all safely contained in the prostate.

At the moment no one knows if you have cancer, but you have enough lesions to justify a biopsy, only then will anyone know if you have cancer.

The fact there is nothing suspicious outside of your prostate means that if this is prostate cancer you will almost certainly be 100% curable.

 

Dave

User
Posted 18 Jul 2025 at 23:06

Hi Michael 

I'm sorry that you've got prostate problems, but welcome to the forum, mate.

I agree with Dave's summation.

The MRI warrants further investigation. You'll probably have a biopsy and the suspicious areas will be targeted to check whether or not they are cancerous and if they are, how aggressive they are likely to be.

Almost 18% of pi rads 4 and 5 lesions (high and very high likely to be clinically significant cancer) turn out to be benign. 

You're bound to be concerned and confused, most of us were. Just take one procedure and one set of results at a time. If you end up being diagnosed with prostate cancer, you'll be given treatment options which you can then focus on.

You'll find lots of help and support here. Please keep us updated and good luck. 👍

 

User
Posted 19 Jul 2025 at 18:24

I had two pirads 4 scoring lesions on my mri scan which wre malteser sized.

I thought that was definitely going to be bad news at biopsy, but there was no sign of cancer.

It is definitely good advice to take this journey one test at a time. Wait for the results and move forward.

Good luck on the biopsy, stay positive above all else.

Mick 

 
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