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Stereotactic Therapy

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User
Posted 01 Sep 2025 at 17:31

Has anybody here had stereotactic radiotherapy for their prostrate cancer?

If so how did it go and what complications or side effects have you had?

Did you have to have any further bi-ops before having the therapy?

I have been on AS for 10 years since 2015, previously with a G6. Repeat bi-ops in 2022 still G6. However, with 2nd lesion developing PSA risen from 3.13 in 2023 to 5.65 in 2025, with a 39% single jump in 2023 to 4.84.

With 3 successive PSA rises can't stay on AS without more bi-ops, so considering stereotactic radiotherapy.

Oncology department saying that I must have further bi-ops before hey will allow me to have treatment, is that correct or necessary? 

I had MRI scan in June 2025 so location and size of lesions known and as far as I understand it you are given the same dose of radiation whether it is a G6, G7, G8 or higher?

User
Posted 02 Sep 2025 at 00:10

Hi there.  I think whatever treatment path you took, they would ideally want to do biopsies to be sure the new lesions they can see on MRI are actually cancerous and what grade. 

User
Posted 02 Sep 2025 at 15:15

If this is the 5 fractions without hormone therapy (rolled out after the successful PACE-B trial), it's limited to T2 G7 (and possibly only 3+4, not 4+3), so they may feel they have to make sure you're still within that category.

PACE-C trial was dealing with higher risk cancer, and adds in hormone therapy, but I haven't seen that treatment rolled out yet.

Standard external beam (20 fractions with hormone therapy) would be applicable for a larger range of diagnoses.

User
Posted 02 Sep 2025 at 16:11
Yes it is the 5 fractions which is why the need to do the bi-ops as it is grade limited at the moment.

My understanding is that it is still in trials, they only started this month, but not sure if they are under PACE-B or C and if the grade limit is G7 or G8?

 
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