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Normal PSA level post Radiotherapy

User
Posted 22 Sep 2025 at 14:20

I have just completed 20 sessions of radiotherapy treatment following a T3a prostate cancer diagnosis with PSA  value of 81.


My PSA value post Radiotherapy has now reduced to 1.7 (8 weeks after radiotherapy finished). 


My oncologist is happy with the post radiation PSA of 1.7, I am continuing with hormone therapy (Prostap injections) and my PSA level will be monitored again in 4 months time and thereafter every 6 months.


Does anyone know what the normal levels are for PSA values post radiotherapy, and NHS guidelines for detecting prostate cancer recurrence in Scotland or UK post treatment?


Currently my oncologist is not offering any MRI or CT scan which is a concern for me given my radiotherapy treatment was rolled out 9months after my original diagnosis.....


I should be grateful if you could share any experiences by replying to this post.


 


Kind Regards 


 


Tom 

User
Posted 22 Sep 2025 at 15:17

Hi Tom, 


I'm not medically trained but as far as I'm aware your PSA drop from 80 to 1.7 is positive news and indicates that the treatment has been affective. I believe that following radiation treatment it can take up to two years to reach your lowest PSA level or nadir.


Here's a Dr Scholz video on monitoring PSA levels following radiotherapy.


https://youtu.be/aUXnlncOiBU?si=dtpJ832V-d84YKhG


Here's NHS Scotland guidelines on follow up procedures.


https://www.woscan.scot.nhs.uk/wp-content/uploads/WoSCAN-Prostate-Cancer-DFUP-Guidance_April-2025_V2.0.pdf


In the UK, I believe BCR is defined as your lowest PSA level + 2ng/ml.


 

Edited by member 22 Sep 2025 at 15:22  | Reason: Additional text

User
Posted 22 Sep 2025 at 15:58

Thanks Adrian for your reply and links to the useful information.


Regards


 


Tom 

User
Posted 23 Sep 2025 at 02:09
It's really the HT that dramatically reduces PSA rather than RT which causes cancer cells to die over time and can't divide to continue. Some cancer cells can be relatively radio-resistant and the process can take longer in some men than others. An early scan after treatment would show little if any difference so this is monitored by PSA.
Barry
User
Posted 23 Sep 2025 at 10:01

Thanks Barry 

User
Posted 24 Sep 2025 at 19:08

Thanks Barry

 
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