Would appreciate info on Cabazitaxel

User

Posted 30 Oct 2025 at 17:34

Hi,

my husband is due to start Cabazitaxel in November. As they haven’t let him know, I would be grateful if somebody could tell me the usual number of cycles for this chemo. As he tolerated Docetaxel well with few side effects he had the full 10 cycles after the original 6 was proposed so I’m wondering whether it will be the same for Cabazitaxel. I understand the side effects are much the same.

They told him that this one is stronger than Docetaxel but they also said it will be at 80% strength and am wondering if this is the usual practice.

Thanks.

User

Posted 12 Nov 2025 at 02:26

Cabazitaxel cycles are usually 6–10, depending on the patient's tolerance and response. It is common practice to use an 80% dose to reduce toxicity, especially when side effects are a concern. The final decision on the number of cycles and dose will be individualized by your doctor based on your husband's medical condition and tolerance to the drug.

Edit by grow a garden a day ago.

Edited by member 13 Nov 2025 at 14:52 | Reason: Not specified

User

Posted 12 Nov 2025 at 06:59

My husband hasn’t had chemo as yet, but at some point I came across some excellent advice for minimising side effects, which I made a mental note of for future reference. If I remember rightly, it involved using ice to protect the mouth from sores, and those foot-warming pads that winter hikers use, to help prevent neuropathy. I hope my message might help jog someone else’s memory and point you towards the original post. Wishing you and your husband all the very best.

User

Posted 12 Nov 2025 at 11:32

Hi bookworm

I had 10 cycles Docetaxel last year and finished my 8th cycle of Cabizitaxel a few months ago,side effects for me were very similar but I felt not as bad.

Unfortunately for me I only received the 8 cycles because progression was seen on mri scans and the sponsors of the trial stopped treatment.

I wish you well on your next treatment.

Phil

User

Posted 16 Nov 2025 at 17:11

Hi Phil,

Thanks for your reply.

I’ve read other people’s comments that they didn’t feel so bad on Cabazitaxel. Peter’s worst ones last time were the oral thrush and strange taste.

I’m sorry it wasn’t as successful for you as hoped. Although Peter had all 10 Docetaxel cycles his PSA only dropped to 6.4 from 95 and started rising again as soon as he’d finished the Docetaxel despite the Zoladex and steroids. The last BT in September showed 27 but it’s probably shot up again since then. The PC was back in the lymph nodes, bone mets too now in femur, rib and clavicle although he’s not in pain at present.

Beginning to wonder how many options are left. Radium 223 has been vaguely mentioned. Meanwhile he starts the Cabazitaxel next week.

Wishing you well on your own journey.

Hazel

User

Posted 16 Nov 2025 at 17:13

Hi ngs99,

Thank you for your reply. I've kept a record of how he coped with the side effects of Docetaxel and am hoping it will be the same for this one as he was quite lucky with them on the whole, apart from the 7th cycle after which they reduced the dose.

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