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User
Posted 27 Dec 2025 at 06:18

Hi everyone,

I’ve just re-joined and wanted to share where I’m at.

 

I had radiotherapy a few years ago and my PSA dropped to 0.03, staying there for four years. About a year after stopping cyproterone acetate, my PSA began rising again — 0.9 → 1.6 → 2.9 over 9 months — so I’m now in recurrence territory with a doubling time of around 6 months. Not easy to process after such a long stable period.

 

I’m booked for an MRI in a couple of weeks and waiting for a bone scan date. I know this isn’t game over, but it’s still a mix of worry and “what next?”

 

If anyone has been through a late PSA rise after radiotherapy, I’d appreciate hearing your experiences.

 

Thanks for having me.

 

User
Posted 28 Dec 2025 at 04:08
Hi,

It may well be that the HT you were having constrained some cancer cells. Then when after you stopped HT these began to be more active resulting in increased PSA which is often the case because a radiated Prostate can still produce PSA. However, in your case it does seem that an MRI and bone scan is prudent and even possibly a PSMA scan in due course. My PSA after RT was stable for a couple of years or so but slowly began to rise thereafter and at an increasing rate. An MRI showed cancer in my Prostate but treatment depended on establishing on whether it was elsewhere. A PSMA scan showed it was only in my Prostate so I had a second HIFU to deal with this. Had it gone elsewhere it might have been possible to treat 2 or 3 cancer hotspots with more radiation and then HIFU the Prostate or remove it but they would not treat my Prostate with HIFU or Prostatectomy until any small spots outside the Prostate had been dealt with. Having said that, hospitals can have slightly different protocols with some allowing more discretion depending on what presents.

Good they are further investigating you but sorry for the need.

Barry
 
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