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Receiving Lutetium 177 Treatment

User
Posted 31 Dec 2025 at 13:36

Hi All

I started Lutetium 177 Treatment back in September. Just thought I would post to try to help with an understanding.

 

I have received both Docetaxel and Cabazitaxel and neither brought any positive results. Please read my profile for more understanding on the progression.

 

Luckily I have private Health Insurance through my employer, so this made the treatment available.

 

14/08/2025 - PET Scan completed to understand if the body will accept the treatment.

18/08/2025 - PET scans positive so treatment to be arranged.

Six cycles to be administered every six weeks.

23/09/2025 - Cycle 1 - PSA 5.18, ALP 304

The treatment takes 2 hours to complete. The treatment is administered and then you receive a scan before leaving to ensure the treatment has been administered throughout the body.

Felt a little nausea during the first week after the treatment. A little off my appetite, by apart from that all was ok.

04/11/2025 - Cycle 2 - PSA 0.5, ALP 224 

No side effects after cycle 2

16/12/2025 - Cycle 3 - PSA 0.43, ALP 216

Again no side effects after treatment, consultant encouraged by the results from bloods taken.

User
Posted 31 Dec 2025 at 13:36

Hi All

I started Lutetium 177 Treatment back in September. Just thought I would post to try to help with an understanding.

 

I have received both Docetaxel and Cabazitaxel and neither brought any positive results. Please read my profile for more understanding on the progression.

 

Luckily I have private Health Insurance through my employer, so this made the treatment available.

 

14/08/2025 - PET Scan completed to understand if the body will accept the treatment.

18/08/2025 - PET scans positive so treatment to be arranged.

Six cycles to be administered every six weeks.

23/09/2025 - Cycle 1 - PSA 5.18, ALP 304

The treatment takes 2 hours to complete. The treatment is administered and then you receive a scan before leaving to ensure the treatment has been administered throughout the body.

Felt a little nausea during the first week after the treatment. A little off my appetite, by apart from that all was ok.

04/11/2025 - Cycle 2 - PSA 0.5, ALP 224 

No side effects after cycle 2

16/12/2025 - Cycle 3 - PSA 0.43, ALP 216

Again no side effects after treatment, consultant encouraged by the results from bloods taken.

User
Posted 01 Jan 2026 at 15:46

Hello Parkie

I have had 177Lu treatment  ...  two doses -  first one 7.6 GBq, second one was 5,5 GBq  -  can you tell us how strong a dose you were given.  Also do you have a PET scan to visualise what is going on.   In my case I have been at psa <0.01 ng/ml for the last six months and the latest PET scan was clear.  Do you have any signs of 'dry mouth'?

Keep us informed and good luck with this.

Crispin

Edited by member 01 Jan 2026 at 15:50  | Reason: Not specified

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User
Posted 31 Dec 2025 at 13:51

Parkie, thanks for the update,info on the lesser used treatments is always useful. I was considered for lut177, but unfortunately a kidney issue meant it wasn't recommended.

Results and tolerance to it look good.Hope it continues to be if benefit going forward.

Thanks Chris 

User
Posted 31 Dec 2025 at 16:50
Hi Parkie,

Thanks for posting this. Very helpful for many of us. So glad to see that the side effects are minimal and 10-fold drop in PSA. Hope the benefits continue, and especially that you can enjoy this holiday season.

User
Posted 01 Jan 2026 at 09:11

Yes i also thankyou for posting and please keep us updated.

Wishing you all the best 👍 

User
Posted 01 Jan 2026 at 15:46

Hello Parkie

I have had 177Lu treatment  ...  two doses -  first one 7.6 GBq, second one was 5,5 GBq  -  can you tell us how strong a dose you were given.  Also do you have a PET scan to visualise what is going on.   In my case I have been at psa <0.01 ng/ml for the last six months and the latest PET scan was clear.  Do you have any signs of 'dry mouth'?

Keep us informed and good luck with this.

Crispin

Edited by member 01 Jan 2026 at 15:50  | Reason: Not specified

 
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